Greiner Bio-One introduces MiniCollect PIXIE for gentle capillary blood collection from infants

Greiner Bio-One introduces MiniCollect Pixie

 

 

MiniCollect® PIXIE is a safety lancet for the heel designed to enhance safety during capillary blood collection from the heel of the youngest patients. With a shallow penetration depth, PIXIE nevertheless gently ensures maximum blood flow. This product is ideal for premature and new-born babies. Three different PIXIE safety lancets are available for heel incision, each adapted to a different stage of infant development. The depth of penetration and the length of incision differ depending on the selected device. Thanks to optimal ergonomics and the fully enclosed blade, MiniCollect PIXIE can enhance safety during capillary blood collection.

Precise incision thanks to tapered lancet slot and dual colour

 When MiniCollect PIXIE is positioned on the heel, the dual colour design, together with the arrows on both sides, allow a precise identification of the puncture site.

  • Ergonomic design and non-slip texture
  • Non-detachable safety tab
  • One-handed activation
  • Trigger positioned on side prevents tissue compression

 

MiniCollect Capillary Blood Collection System

 MiniCollect offers a gentle way to collect small blood samples for analyses.

The system is perfectly suited for young children, geriatric patients as well as patients with fragile veins. MiniCollect is also recommended in situations where venous blood collection proves particularly difficult or contraindicated.

For delicate vein conditions, patients who often have blood samples taken, or people with severe burns, capillary blood collection with the MiniCollect system offers a great alternative to venous blood collection.

The MiniCollect tube includes an integrated scoop, allowing droplets of blood to be collected easily and hygienically. To ensure that the puncture wound can be kept as small as possible while achieving the targeted sample volume there are different lancets with a wide range of puncture depths and blade sizes / needle gauges available.

doctor

WHO’s Council on the Economics of Health for All issues brief on equitable health innovation

Leading economists and health experts call for a health innovation ecosystem governed by “the common good”

surgery

The WHO Council on the Economics of Health for All, which comprises leading economists and health experts from across the globe, has called on governments, the scientific and medical community and private sector leaders to re-design the health innovation ecosystem toward delivering health technologies for the common good.

In the Council’s first brief, its members called on the public and private sectors to work collaboratively to deliver needed vaccines, therapeutics, diagnostics, and other essential health supplies that are available equitably to those who can benefit.

The Council Brief recommends both immediate and long-term action, urging all stakeholders to work towards creating a health innovation ecosystem characterized by purpose-driven and symbiotic public-private partnerships that put the common good front and centre.

“Mobilizing money to throw at solutions that fail to address the underlying causes of longstanding structural problems will not be sufficient,” according to the Council Brief. “We all must look forward towards re-imagining health innovation as part of a new economic ecosystem that can deliver Health for All.”

Deep change is needed

The Council has made clear that just patching up the existing system will not work. Deep change is needed on how intellectual property rights are governed to drive collective intelligence, how corporate governance is structured, and how the benefits of public investments are shared to avoid the current dynamic of sharing risks but privatizing rewards.

To build an inclusive end-to-end health innovation ecosystem able to deliver the appropriate medical technologies required to achieve Health for All equitably, the following building blocks are critical:

  • Creating purpose-driven innovation through a mission-oriented approach;
  • Reshaping knowledge governance to nurture collective intelligence;
  • Reforming corporate governance to be more long-term and purpose-oriented;
  • Building resilient manufacturing capacity and infrastructure;
  • Introducing conditionalities for public investments to build symbiotic public-private partnerships;
  • Strengthening the capacity of the public sector on both the supply and demand side.

Growing calls for urgent action

In the short-term, the Council, in its brief, adds its voice to the growing calls for urgent action in four areas:

  • Available vaccine doses should be redistributed immediately, not as acts of charity, but as a shared imperative for pandemic control and inclusive, equitable and sustainable access.
  • Technology transfer and building manufacturing capacity must be supported and financed, not as the responsibility or property of any single actor, but as a collective responsibility towards building health greater health security and resilience in all regions, governed as common goods.
  • Knowledge should not be kept as privatized intellectual property under monopoly control but considered collective rewards from a collective value creation process to be openly shared and exchanged.
  • Existing mechanisms set up to address the above aspects, including COVAX, ACT-Accelerator, and the Covid Technology Access Pool, should be utilized and strengthened, not as an approach to fix market failures, but as turning points for creating market-shaping approaches.”

The Council’s brief came ahead of the G7 Leaders’ Summit under the U.K.’s Presidency, which aims to build back better from the COVID-19 pandemic, including by strengthening resilience against future pandemics; and following the Seventy-fourth World Health Assembly and the G20 Global Health Summit co-hosted by Italy and the EU earlier this month.

The Council, which was established by the World Health Organization in November 2020, is chaired by noted economist Professor Mariana Mazzucato, Professor of the Economics of Innovation and Public Value and Founding Director in the Institute for Innovation and Public Purpose at University College London.

Its patron is H.E. Sanna Marin, Prime Minister of Finland.

Carestream offers new floor-mount option for DRX-Compass X-ray system

Carestream offers new floor-mount option for DRX-Compass X-ray system

The Carestream DRX-Compass X-ray System

 

Carestream Health is providing healthcare facilities with a new floor-mount option for the DRX-Compass X-ray System. This option delivers an innovative, flexible and efficient medical imaging solution to sites that are unable to accommodate an overhead tube crane.

It is ideal for community, rural and private hospitals. It is also well suited for urgent care centers, orthopaedic and large radiology practices.

A good option for smaller budgets

“The free-standing tube mount eliminates the need for ceiling rails, but still provides the wall stand, table and console features, the same as the overhead tube crane,” said Jing Chu, Worldwide Product Marketing Manager at Carestream.

“This option will offer smaller facilities or sites with tighter budgets the ability to use the DRX-Compass and put Carestream’s exceptional image capture and processing to work.”

Advanced features

The Carestream DRX-Compass X-ray System (see video of DRX-Compass system) is an upgrade-friendly unit with a broad array of advanced features and options to meet changing needs. It has vertical auto-tracking and auto-centring, as well as an optional tilting wall stand to support a wide range of exams. Developed for easy positioning, this system was designed to decrease set-up time and increase throughput for every facility. Its intuitive, graphical user interface reduces training time for radiographers and allows for a secure, swipe-and-go login. The auto long-length imaging option is especially useful for patients who have trouble standing or young children who are unable to hold still for long periods of time.

“Whatever your modality right now, and wherever you need to go in the future, we have the upgrade strategy to get you there – seamlessly,” Chu said. “The DRX-Compass is designed to keep costs in line with a facility’s needs by being scalable and upgradable.”

Bridge to move from analogue to digital

With the ability to select components for specific locations, the system can easily adapt to space requirements. The DRX-Compass offers a bridge for healthcare facilities looking to move from an analogue or retrofitted X-ray room to a digital system. Through Carestream’s ImageView clinical acquisition software, powered by Eclipse image processing, healthcare facilities can add capabilities to their DRX-Compass systems as needed over time.

Crohns mouse model

Researchers create bioengineered organism that could diagnose Crohn’s disease flareups

Jeff Tabor, associate professor of bioengineering in Rice’s Brown School of Engineering

Jeff Tabor, associate professor of bioengineering in Rice’s Brown School of Engineering (Credit: Jeff Fitlow/Rice University)

In an important step toward the clinical application of synthetic biology, Rice University researchers have engineered a bacterium with the necessary capabilities for diagnosing a human disease.

The engineered strain of the gut bacteria E. coli senses pH and glows when it encounters acidosis, an acidic condition that often occurs during flareups of inflammatory bowel diseases like colitis, ileitis and Crohn’s disease.

Crohns mouse model

Rice University researchers engineered a strain of the gut bacteria E. coli to detect gastrointestinal acidosis. The organism produces fluorescent molecules that allow researchers to see it with standard optical equipment. Under normal conditions (left) it produces molecules that glow red. When it encounters acidic conditions (right), it glows green, and the brightness of the glow reflects the level of acidity. (Image courtesy of Jeff Tabor/Rice University)

Researchers at the University of Colorado (CU) School of Medicine used the Rice-created organism in a mouse model of Crohn’s disease to show acidosis activates a signature set of genes. The corresponding genetic signature in humans has previously been observed during active inflammation in Crohn’s disease patients. The results are available online in the Proceedings of the National Academy of Sciences.

Colours that show up in the toilet

Study co-author Jeffrey Tabor, whose lab engineered the pH-sensing bacterium, said it could be reprogrammed to make colours that show up in the toilet instead of the fluorescent tags used in the CU School of Medicine experiments.

“We think it could be added to food and programmed to turn toilet water blue to warn patients when a flareup is just beginning,” said Tabor, an associate professor of bioengineering in Rice’s Brown School of Engineering.

Over their 3.5 billion-year history, bacteria have evolved countless specific and sensitive genetic circuits to sense their surroundings. Tabor and colleagues developed a biohacking toolkit that allows them to mix and match the inputs and outputs of these bacterial sensors. The pH-sensing circuit was discovered by Rice Ph.D. student Kathryn Brink in a 2019 demonstration of the plug-and-play toolkit.

pH sensor

PNAS study co-authors Sean Colgan, the director of the CU School of Medicine’s mucosal inflammation program, and Ian Cartwright, a postdoctoral fellow in Colgan’s lab, read about the pH sensor and contacted Tabor to see if it could be adapted for use in a mouse model of Crohn’s disease.

“It turns out that measuring pH within the intestine through noninvasive ways is quite difficult,” said Colgan, the Levine-Kern Professor of Medicine and Immunology in the CU School of Medicine.

So Brink spent a few weeks splicing the necessary sensor circuits into an organism and sent it to Colgan’s lab.

“Normally, the pH in your intestines is around seven, which is neutral, but you get a lot of inflammation in Crohn’s disease, and pH goes to something like three, which is very acidic,” Tabor said.

Colgan and colleagues have studied the genes that are turned on and off under such conditions and “needed a tool to measure pH in the intestine to show that the things they were observing in in vitro experiments were also really happening in a live animal,” Tabor said.

Biological tool

“Colonizing this bacterial strain was the perfect biological tool to monitor acidosis during active inflammation,” Colgan said. “Correlating intestinal gene expression with the bacterial pH sensing bacteria proved to be a useful and valuable set of biomarkers for active inflammation in the intestine.”

Tabor said he believes the pH-sensing bacterium could potentially be advanced for human clinical trials in several years.

more nurses leads to shorter patient stays

More nurses lead to shorter hospital stays, less readmissions and fewer patient deaths

Australian study shows that savings made from shorter stays are double the cost of hiring more staff

more nurses lead to fewer patient deaths

 

 

 

 

 

 

 

 

 

 

 

 

 

A study across 55 hospitals in Queensland, Australia suggests that a recent state policy to introduce a minimum ratio of one nurse to four patients for day shifts has successfully improved patient care, with a 7% drop in the chance of death and readmission, and 3% reduction in length of stay for every one less patient a nurse has on their workload.

The study of more than 400,000 patients and 17,000 nurses in 27 hospitals that implemented the policy and 28 comparison hospitals is published in The Lancet. It is the first prospective evaluation of the health policy aimed at boosting nurse numbers in hospitals to ensure a minimum safe standard and suggests that savings made from shorter hospital stays and fewer readmissions were double the cost of hiring more staff.

Despite some evidence that more nurses in hospitals could benefit patient safety, similar policies have not been widely implemented across the globe, partly due to an absence of data on the long-term effects and costs, as well as limited resources. In recent years, Scotland, Wales, and Ireland have mandated numbers of patients per nurse, but strategies to improve nursing levels remains debated worldwide.

Study fills data gap

“Our findings plug a crucial data gap that has delayed a widespread roll-out of nurse staffing mandates. Opponents of these policies often raise concerns that there is no clear evaluation of policy, so we hope that our data convinces people of the need for minimum nurse-to-patient ratios by clearly demonstrating that quality nursing is vital to patient safety and care,” says lead author, Professor Matthew McHugh of the University of Pennsylvania School of Nursing, USA.

In 2016, 27 public hospitals in Queensland were required to instate a minimum of one dedicated nurse for every four patients during day shifts and one for every seven patients for night shifts on medical-surgical wards.

The research team collected data from those 27 Queensland hospitals that instated ratios and from 28 other hospitals in the state that did not, at baseline in 2016 and at follow-up in 2018 (two years after the policy was implemented). Only nurses in direct contact with adult patients in medical-surgical wards were included – data from patients in birthing suites and psychiatric units were not assessed in the study.

Researchers used patient data to assess demographics, diagnoses, and discharge details for patients, as well as length of hospital stay. These data were then linked to death records for 30 days following discharge, and to readmissions within seven days of discharge.

The researchers sent an email survey to nurses in each hospital to ask about the numbers of bedside nurses and patients on their most recent shift. The responses were used to establish the numbers of nurses per patient and then averaged across wards and hospitals. Responses were received from 8,732 nurses (of a possible 26,871) at baseline in 2016, and 8,278 (of a possible 30,658) in 2018.
more nurses leads to shorter patient stays

The study includes baseline data for 231,902 patients (142,986 in hospitals that implemented the policy and 88,916 in comparison hospitals), and for 257,253 patients (160,167 in hospitals that implemented the policy and 97,086 in comparison hospitals) after the policy was brought in.

Comparison hospitals had no change in staffing, with six patients per nurse in 2016 and the same ratio (1:6) in the follow-up period in 2018. Intervention hospitals averaged five patients per nurse at baseline in 2016, with a reduction to four per nurse after the policy implementation.

Patient deaths

To compare the changes in outcomes in the intervention and comparison hospitals over time, the researchers estimated the odds of dying within 30 days of admission and of being readmitted within seven days of discharge, and the additional length of stay, after adjusting for factors such as patient age, sex, existing health conditions and hospital size. They found that the chance of death rose between 2016 and 2018 by 7% in hospitals that did not implement the policy, and fell by 11% in hospitals that did implement the policy.

Readmissions

The chances of being readmitted increased by 6% in the comparison hospitals over time, but stayed the same in hospitals that implemented the policy. Between 2016 and 2018, the length of stay fell by 5% in the hospitals that did not implement the policy, and by 9% in hospitals that did.

Nurse workloads

Further analyses found that when nurse workloads improved by one less patient per nurse, the chance of death and readmissions fell by 7%, and the length of hospital stay dropped by 3%.

Using their modelling to predict figures that would have been expected without the policy in place, the researchers estimated that there could have been 145 more deaths, 255 more readmissions and 29,222 additional days in hospital in the 27 hospitals that implemented the policy between 2016 and 2018.

Financial impact of employing more nurses

To calculate the financial impact of the staffing policy, the researchers used state data to estimate the cost of funding the 167 extra staff needed to reduce workload by one patient per nurse at approximately $33,000,000 (AUD) in the first two years. Based on Australian health economic data, they further estimated that preventing readmissions and reducing lengths of stay resulted in an approximate saving of $69,150,858 in the 27 hospitals across the two years following the mandate.

“Part of the reluctance to bring in a minimum nurse-patient ratio mandate from some policy-makers is the expected rise in costs from increased staffing. Our findings suggest that this is short-sighted and that the savings created by preventing readmissions and reducing length of stay were more than twice the cost of employing the additional nurses needed to meet the required staffing levels – a clear return on investment. Often, policy-makers are concerned about whether they can afford to implement such a policy. We would encourage governments to look at these figures and consider if they can afford not to,” says Professor Patsy Yates of the Queensland University of Technology School of Nursing, Australia.

Study limitations

The authors note that there are a number of limitations associated with the study. Hospitals in the research were not randomly assigned to comparison or intervention groups, as only 27 hospitals in the state were mandated to follow the policy. Furthermore, the hospitals included in both groups were not matched for size or patient demographics and health conditions, although this is accounted for in adjusted analyses.

Access the study: Effects of nurse-to-patient ratio legislation on nurse staffing and patient mortality, readmissions, and length of stay: a prospective study in a panel of hospitals. The Lancet. May 11, 2021. https://doi.org/10.1016/S0140-6736(21)00768-6

covid-19 vaccination

COVID vaccines: some fully vaccinated people will still get infected – here’s why

covid-19 vaccination

 

By Tara Hurst  
Lecturer, Biomedical Science, Birmingham City University

 

The development of several COVID vaccines in less than a year has given us all hope of a release from the pandemic. Now the goal has shifted to ensuring widespread vaccine coverage is achieved as quickly as possible around the globe.

However, it is unlikely that any of the vaccines will be 100% effective at stopping transmission or infection. There is a small risk that some fully vaccinated people will get infected. This is known as a “breakthrough infection” – and it’s entirely expected.

It is important to realise the limitations of vaccines. No vaccine offers full protection to everyone who receives it. The measles vaccine has been highly effective at preventing infection, leading to the virus being nearly eradicated in some countries.

Yet there are infections reported even in populations with widespread vaccination. These infections occur not only in the unvaccinated; there are cases of breakthrough infections in fully vaccinated people.

The seasonal flu vaccine offers protection from the circulating viruses. But the circulating flu viruses vary, and vaccinated people may still get ill but have less severe illness.

This is possibly because different arms of the immune response produce different defences, namely antibodies, which are Y-shaped proteins that lock onto germs and neutralise them, and T cells, which find and destroy infected cells. Antibodies are typically raised against the more variable proteins on the surface of the virus, while the more consistent proteins inside the virus are targeted by the T cells. T cells are important for limiting the severity of illness.

For SARS-CoV-2 (the virus that causes COVID-19) there is anecdotal evidence, including from Seychelles, of breakthrough infections, but little has yet been published in scientific journals. A recent report in the New England Journal of Medicine described two COVID-19 cases following vaccination, with both showing mild symptoms that resolved within one week.

And a study from Stanford University, which is yet to be reviewed by other scientists, describes 189 post-vaccination COVID cases out of 22,729 healthcare workers, but attributes at least some of these to partial vaccination. Vaccination will probably make the disease less severe should such breakthroughs occur.

Several explanations

There are several possible explanations for breakthrough infections. The human immune response is encoded in our DNA and varies from person to person. This variability helps us to respond to an array of germs. But the effectiveness of these responses is also variable. This could also be due to several things, including poor health, medication or age.

The ageing immune system does not respond to new antigens (foreign substance that causes your immune system to produce antibodies against it) and vaccines as well as younger immune systems. For one COVID vaccine, there was a measurable difference in the concentration of neutralising antibodies in the elderly compared with younger adults. Some of the elderly participants had no neutralising antibodies at all after both doses of the vaccines.

Another reason for breakthrough infections is due to viral variants that escape immune detection and flourish even in vaccinated people. A virus, especially an “RNA virus” such as SARS-CoV-2, is expected to mutate and give rise to variants, some of which may be more easily transmitted. These variants may also be more or less effectively neutralised by the immune system since the mutations could alter the parts of the virus that are recognised by antibodies and T cells.

A new SARS-CoV-2 variant identified in India (B16172) is thought to make the virus more transmissible and this is a cause for concern in light of the COVID crisis unfolding there. Despite the absence of scientific studies, there are many reports in the media of frequent breakthrough infections and the B16172 variant is blamed, but this has yet to be proved.

In the one study, done on post-vaccine infections with SARS-CoV-2 in California, there was no significantly higher risk of infection due to the variants circulating in that region. Despite the evidence that the vaccines work well against the variants, the rapid increase in the proportion of cases in the UK that are due to B16172 as compared to the dominant Kent strain (B117) has meant that it has been raised to a variant of concern by Public Health England.

While widespread vaccination remains the pandemic end game, it bears mentioning that this is unlikely to prevent all infections. Those who develop COVID after vaccination will probably have a milder illness, and so the risk of breakthrough infections should not deter us from using the current vaccines. Further study into the causes of breakthrough SARS-CoV-2 infections could help scientists to refine COVID vaccines or the schedule of booster doses.

brain-to-text BCI

Brain-to-text: Researchers develop brain-computer interface that turns neural signals into typed text in real time

brain-to-text BCI

Thoughts turned into text: Two implanted electrode arrays record the brain activity produced by thinking about writing letters. This information is then collected and processed in real-time by a computer, which converts that data into words on a screen. Courtesy Shenoy lab & Erika Woodrum (artist)

 

Scientists have developed a brain-computer interface (BCI) which for the first time enables neural signals associated with handwriting to be decoded and turned into text in real time.

This breakthrough in BCI technology has the potential to enable paralysed or paraplegic individuals – unable to write or speak – to communicate in writing, at speed, in real time.

The study was published in Nature, May 12.

The researchers developed an intracortical BCI that decodes attempted handwriting movements from neural activity in the motor cortex and translates it to text in real time, using a recurrent neural network decoding system.

They tested the device in a participant with paralysis which in essence enabled him to type without using his hands. By thinking about handwriting letters, the researchers were able to decode the neural signals with an algorithm which turned the letters into typed text on a screen in real time.

The study participant typed 90 characters per minute – more than double the previous record for typing with such a BCI. However, previous studies had not used decoded neural handwriting signals. They had instead used thought-controlled cursor movements on a virtual keyboard.

Neural signals associated with handwriting

Study coauthor Krishna Shenoy, a Howard Hughes Medical Institute (HHMI) investigator at Stanford University and his team have in recent years been studying neural activity associated with speech in an effort to reproduce it. However, they had not considered trying to decode neural signals associated with handwriting, says Frank Willett, an HHMI research specialist and neuroscientist in Shenoy’s group.

First, the participant was asked to copy letters that were displayed on the screen, which included the 26 lower-case letters along with some punctuation: “>” which was used as a space and “~” which was used as a “full stop.” At the same time, implanted electrodes recorded the brain activity from approximately 200 individual neurons associated with handwriting that responded differently while he mentally “wrote” each individual character. After a series of training sessions, the BCI’s computer algorithms learned how to recognize neural patterns corresponding to individual letters, allowing the participant to “write” new sentences that hadn’t been printed out before, with the computer displaying the letters in real time.

“This method is a marked improvement over existing communication BCIs that rely on using the brain to move a cursor to ‘type’ words on a screen,” said Willett, the study’s lead author. “Attempting to write each letter produces a unique pattern of activity in the brain, making it easier for the computer to identify what is being written with much greater accuracy and speed.”

Level of flexibility

This system also provides a level of flexibility that is crucial to restoring communication. Some studies have gone as far as attempting direct thought-to-speech BCIs that, while promising, are currently limited by what is possible through recordings from the surface of the brain which averages responses across thousands of neurons.

“Right now, other investigators can achieve about a 50-word dictionary using machine learning methods when decoding speech,” said Dr. Shenoy. “By using handwriting to record from hundreds of individual neurons, we can write any letter and thus any word which provides a truly ‘open vocabulary’ that can be used in almost any life situation.”

Although it is still relatively early days for this technology, it offers the potential to help those who have completely lost the ability to write and speak.

In the future, Dr. Shenoy’s team intends to test the system on a patient who has lost the ability to speak, such as someone with advanced ALS. In addition, they are looking to increase the number of characters available to the participants (such as capital letters and numbers).

The participant is part of a clinical trial, called BrainGate2, which is being conducted by a collaboration of internationally recognized laboratories, universities, and hospitals working to advance brain-computer interface technologies.

 

Reference

Willett, F.R., Avansino, D.T., Hochberg, L.R. et al. High-performance brain-to-text communication via handwriting. Nature 593, 249–254 (2021). https://doi.org/10.1038/s41586-021-03506-2

14-year-old becomes youngest patient to receive living donor liver transplant at Cleveland Clinic Abu Dhabi

live liver donor transplant

 

A 14-year-old boy has received a living liver donation from his elder brother at Cleveland Clinic Abu Dhabi, an integral part of Mubadala Health, becoming the youngest patient to undergo the operation in the hospital’s history.

Montasir Elfatih Mohyeldin Taha was diagnosed with biliary atresia in infancy, a condition where the bile ducts outside the liver fail to form during fetal development, not allowing the bile to reach the small intestine where it helps in the digestion of fat. At 10 months, he had to undergo the Kasai procedure, which is done to connect a loop of small bowel directly to the liver so that the bile can drain into it. Montasir’s doctors back home in Sudan knew that it was only a matter of time before he would have to undergo a liver transplant, an inevitable consequence for most children who have this procedure.

Portal hypertension

Earlier this year, Montasir’s symptoms and blood tests revealed that he had started developing liver failure and was suffering from portal hypertension, an increase in the pressure within the vein that carries blood from the digestive organs to the liver, resulting in varicose veins in his esophagus. Seeing the high risk of potential complications, his doctors in Sudan recommended that he undergo a liver transplant at Cleveland Clinic Abu Dhabi.

Dr. Luis Campos, the Director of Liver Transplant and Hepatobiliary at Cleveland Clinic Abu Dhabi, who was part of the interdisciplinary team that cared for Montasir, says this was one of the most complex living donor liver transplant surgeries that they have performed at the hospital.

“There were additional nuances that had to be taken into consideration because of his age, which made it even more challenging. Factors such as height and weight impact the surgery and after-care, and determine the dose of immunosuppressive medication during and after the transplant. There is also a risk of other infectious complications in pediatric liver transplant that do not apply to adult surgeries,” says Dr. Campos.

Multidisciplinary medical team

The multidisciplinary medical team at Cleveland Clinic Abu Dhabi studied the case and evaluated Montasir’s mother and brother for a match in February. After careful discussion with colleagues in the US-based Cleveland Clinic, doctors here decided that his sibling would be a more suitable match.

“My little brother needed me. I was very relieved when I was told that I can help be the cure to his illness. This was one of the easiest decisions that I have had to make,” says Khalifa Elfatih Mohyeldin Taha. “My father passed away six months back and as the eldest son in the family, it was my responsibility to save him.”

Kasai procedure

Dr. Shiva Kumar, the Chair of Gastroenterology and Hepatology in the Digestive Disease Institute at Cleveland Clinic Abu Dhabi, who was also part of the patient’s care team, says one of the biggest challenges during Montasir’s transplant was posed by the young patient’s Kasai procedure.

“While the Kasai procedure is commonly performed to prolong the need for a liver transplant in children, this is a major operation and makes the transplant more challenging to perform,” says Dr. Kumar.

“However, the surgeries of both brothers were successful and without complications. Montasir received a left lobe graft from his brother. This is a smaller portion of the liver than if we were transplanting a right lobe graft. This makes it a safer operation for the donor and helps them recover faster.”

Immunosuppressive regimen

The brothers are on their way to a full recovery. Khalifa is back to his normal life now while the Cleveland Clinic Abu Dhabi care team is monitoring Montasir’s immunosuppressive regimen, which he will be on for the rest of his life.

Khalifa says he could not contain his joy when he was told that the surgery was a success. “The best part of my transplant journey was to see that Montasir’s body had accepted the new organ. My family and I are very grateful to the care team at Cleveland Clinic Abu Dhabi for saving my brother’s life.”

He also hopes that more people consider organ donation. “The feeling of giving a chance to someone to live a normal life is incomparable. Seeing the result of your donation will fill you with contentment.”

Yosi Health - virtual waiting room

Yosi Health’s patient intake solution selected by Henry Schein Medical Systems to create virtual waiting room

 

Yosi Health - virtual waiting room

Yosi Health, a provider of digital patient scheduling, registration, payment, and communication cloud-based software solutions, has been selected by Henry Schein Medical Systems.

Henry Schein Medical Systems, a subsidiary of Henry Schein and developer of MicroMD, will integrate Yosi’s patient intake solution, Yosi Intake, with their practice management and electronic medical record software.

Contactless waiting room

Yosi Intake can create a contactless waiting room by enabling patients to register at home, helping to improve the patient experience and reduce administrative costs for the practice. The solution can help eliminate wait times and enhance the patient experience for small to large clinical practices.

“The COVID-19 pandemic has forced healthcare practices to dramatically rethink the way they interact with patients,” said Hari Prasad, CEO of Yosi Health. “Yosi Health allows these practices to streamline the patient intake process, which gives patients the assurance and confidence they need to keep current with their regularly scheduled office visits.”

MicroMD

Serving more than 10,000 physicians in primary care, as well as all major medical and surgical specialties, MicroMD offers practices a portfolio of integrated medical software solutions, including electronic claims management, accounts receivable management, patient registration and scheduling, and reporting. In addition, the portfolio includes an intuitive electronic medical record system with streamlined encounter capture and multiple charting methods.

“Yosi Health provides an exceptional, end-to-end patient experience that shoulders most of the administrative and document management load for client facilities,” explained Kristen Heffernan, General Manager at MicroMD. “Together with Yosi Health, we are helping providers reimagine healthcare, leveraging integrated technology that changes the way practices keep their patients and staff safe and modernizes the care delivery experience.”

Hologic introduces 3D breast ultrasound imaging on SuperSonic MACH Systems in Europe

Hologic has made available in Europe 3D ultrasound imaging on the SuperSonic MACH 30 and 20 ultrasound systems. This innovation gives clinicians access to high-resolution B-mode and ShearWave PLUS elastography 3D volumes, providing additional insights and enhancing diagnostic certainty.