Dr Bipin Patel, CEO and Founder electronRx

electronRx launches pDx app for remote lung monitoring

Cambridge-based digital medicine company electronRx has announced the launch of pDx, a medical-grade application designed to enable remote monitoring of chronic respiratory diseases through smartphone, laptop, or tablet devices. The technology will debut at HLTH 2025 in Las Vegas (19–22 October), offering clinicians new capabilities for assessing cardiopulmonary function without requiring in-person consultations.

reducing unnecessary preoperative testing

Hospital teams reduce unnecessary preoperative testing by tailoring strategies to local workflows

A tailored, multi-faceted intervention has achieved substantial reductions in wasteful pre-surgery testing across Michigan hospitals, demonstrating that education, teamwork and site-specific adaptation can eliminate low-value care whilst preserving patient safety. The RITE-Size programme reduced unnecessary testing rates from 68% to 40% over six months across three hospital settings.

GE HealthCare’s Revolution Vibe CT

GE HealthCare’s Revolution Vibe CT receives FDA clearance

GE HealthCare has secured FDA 510(k) clearance for its Revolution Vibe CT system, a cardiac imaging platform designed to capture full-heart clarity in a single beat without requiring electrocardiogram trace. The system addresses growing demand for coronary CT angiography (CCTA) as cardiovascular disease continues to account for projected annual deaths exceeding 23 million globally by […]

Billy Boyle, co-founder and CEO, Owlstone Medical

Owlstone Medical secures $49.1 million ARPA-H award

Cambridge-based breath diagnostics specialist Owlstone Medical has been awarded up to $49.1 million by ARPA-H to develop at-home multi-cancer early detection tests. The POSEIDON programme aims to detect 30+ solid tumours at Stage I using synthetic biosensors analysed through breath and urine samples, addressing critical gaps in accessible cancer screening.

First pig-to-human liver transplant reported

A landmark case published in the Journal of Hepatology describes the world’s first auxiliary liver xenotransplant from a genetically engineered pig to a living human recipient, with the patient surviving 171 days. The procedure demonstrates that genetically modified porcine livers can support essential hepatic functions in humans, whilst highlighting significant complications that must be addressed […]

paediatric CNS biorepository established in US partnership

Novel paediatric CNS biorepository established in US partnership

COMBINEDBrain and the Medical University of South Carolina have announced a strategic collaboration to establish what they describe as the first biorepository dedicated to paediatric central nervous system tissue and cerebrospinal fluid from neurotypical donors, addressing a significant gap in neurological disease research infrastructure.

dendritic nanotubes in the brain

Scientists discover hidden neural network that may drive early Alzheimer’s disease

Researchers have identified dendritic nanotubes – ultrathin connections between neurons that can transport disease-related proteins. The structures, distinct from conventional synapses, may accelerate toxic protein accumulation in specific brain cells during early Alzheimer’s pathology, offering potential new therapeutic targets.

osteoporosis

Mechanosensitive receptor offers new approach to osteoporosis treatment

Researchers have identified GPR133/ADGRD1, a mechanosensitive adhesion G protein-coupled receptor, as a promising therapeutic target for osteoporosis. The receptor responds to both mechanical forces and molecular signals, enhancing bone formation through cAMP-dependent activation of β-catenin signalling. A novel small-molecule agonist significantly alleviated osteoporosis in preclinical models, suggesting potential for clinical development.

patient perspectives

Patients identify six key areas for surgeon communication

A systematic review of patient perspectives reveals that cancer patients prioritise emotional support, optimistic demeanour, and realistic expectation-setting from their surgical oncologists alongside clinical expertise. The research identifies six distinct communication domains that shape patient satisfaction and treatment adherence.

Mayo Clinic

Mayo Clinic launches AI-powered clinical development platform leveraging international partner ecosystem

Mayo Clinic has launched Mayo Clinic Platform_Orchestrate, a comprehensive programme designed to accelerate clinical development by providing biopharma and medical device companies with streamlined access to de-identified clinical data, artificial intelligence tools, and international research networks.