Scientists at the University of Cambridge have created three-dimensional embryo-like structures that produce blood stem cells through a naturally occurring developmental process, eliminating the need for supplementary growth factors. The innovation, termed ‘hematoids’, mimics human embryonic blood development and could transform approaches to regenerative medicine and disease modelling.
Researchers at the University of Minnesota Twin Cities have demonstrated a groundbreaking process that combines 3D printing, stem cell biology, and lab-grown tissues for spinal cord injury recovery. The innovative approach uses microscopic channels to guide neural regeneration, offering new hope for treating complete spinal cord injuries.
New research reveals a rapid regenerative pathway activated minutes after liver injury through glutamate signalling between liver and bone marrow, offering potential therapeutic applications for liver damage.
Korean researchers have developed a breakthrough gene therapy that restores vision loss caused by retinal degeneration. The therapy works by neutralising a protein called Prox1 that suppresses retinal regeneration. When the Prox1 protein is blocked, Müller glial cells in the retina can reprogram into stem-like cells that regenerate damaged neurons, restoring visual function.
Scientists have discovered two populations of stem cells in the retina with strong regenerative properties, according to a new study published in Science Translational Medicine. The research team identified human neural retinal stem-like cells (hNRSCs) that can differentiate into light-sensing cells, offering a potential source of stem cells for regenerative eye therapies.
Novel stimulation protocol helps reduce muscle spasticity and improve walking rehabilitation in patients with incomplete spinal cord injuries, offering hope for enhanced recovery outcomes.
Researchers at the University of Nottingham have developed a new approach to create regenerative materials using patients’ own blood, combined with synthetic peptides, demonstrating successful bone repair in animal studies.
A groundbreaking study has mapped prenatal human skin at the cellular level, offering unprecedented insights into skin formation and hair follicle development. The research, which includes the creation of a novel skin organoid model, could pave the way for developments in treating congenital skin disorders and improving regenerative medicine approaches.
New research reveals how delaying inflammatory signalling can dramatically increase the number of blood stem cells formed during embryonic development, potentially aiding efforts to produce these cells in the laboratory.
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Jitesh Neupane, University of Cambridge
McAlpine Research Group, University of Minnesota
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© Clyde Campbell