Scientists have created the first comprehensive map showing how human DNA is mixed and passed down through generations, offering new understanding of genetic diversity and its relationship to fertility and evolution.
UCLA Health study demonstrates significant impact of genetic diagnostics on treatment decisions and specialist referrals in complex neurodevelopmental cases, pointing towards more personalised medical approaches.
A groundbreaking RNA-based technology allows therapeutic genes that are too large for conventional delivery methods to be successfully transported into cells, offering new hope for treating muscular dystrophies and other genetic disorders caused by mutations in large genes.
New research challenges long-held beliefs about the causes of gout, highlighting the significant impact of genetics on the chronic inflammatory condition.
New research reveals how delaying inflammatory signalling can dramatically increase the number of blood stem cells formed during embryonic development, potentially aiding efforts to produce these cells in the laboratory.
Researchers at The Rockefeller University have identified a rare genetic mutation that increases vulnerability to tuberculosis, potentially reshaping our understanding of tumour necrosis factor’s role in the immune system.
A groundbreaking MIT study published in Nature offers new insights into the cellular mechanisms underlying Alzheimer’s disease, revealing potential targets for interventions to maintain cognitive function.
Scientists in the UK have developed the first code of practice for research using stem cell-based embryo models, providing ethical guidelines and governance for this rapidly advancing field.
A groundbreaking gene therapy for Duchenne muscular dystrophy (DMD) has demonstrated significant potential in not only arresting muscle decline but also possibly repairing damaged muscle tissue. This novel treatment, developed by researchers at UW Medicine, utilises a series of protein packets delivered via viral vectors to replace the defective DMD gene within affected muscles.
Research from Mass Eye and Ear demonstrates successful use of CRISPR/Cas9 to target and disrupt a genetic mutation causing hearing loss, offering hope for future treatments in humans.
April 2024
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© Clyde Campbell
Tsai Lab/ MIT Picower Institute
Irene Zorzan and Teresa Rayon, Babraham Institute
Chamberlain Lab