New research challenges long-held beliefs about the causes of gout, highlighting the significant impact of genetics on the chronic inflammatory condition.
New research reveals how delaying inflammatory signalling can dramatically increase the number of blood stem cells formed during embryonic development, potentially aiding efforts to produce these cells in the laboratory.
Researchers at The Rockefeller University have identified a rare genetic mutation that increases vulnerability to tuberculosis, potentially reshaping our understanding of tumour necrosis factor’s role in the immune system.
A groundbreaking MIT study published in Nature offers new insights into the cellular mechanisms underlying Alzheimer’s disease, revealing potential targets for interventions to maintain cognitive function.
Scientists in the UK have developed the first code of practice for research using stem cell-based embryo models, providing ethical guidelines and governance for this rapidly advancing field.
A groundbreaking gene therapy for Duchenne muscular dystrophy (DMD) has demonstrated significant potential in not only arresting muscle decline but also possibly repairing damaged muscle tissue. This novel treatment, developed by researchers at UW Medicine, utilises a series of protein packets delivered via viral vectors to replace the defective DMD gene within affected muscles.
Research from Mass Eye and Ear demonstrates successful use of CRISPR/Cas9 to target and disrupt a genetic mutation causing hearing loss, offering hope for future treatments in humans.
New research from Johns Hopkins University expands our understanding of genetic variation across diverse populations, potentially improving the accuracy of genetic predictions and personalised medicine.
Researchers have developed a novel gene-editing approach that efficiently corrects the most common cystic fibrosis mutation, potentially paving the way for a one-time, permanent treatment with fewer side effects than current therapies.
A groundbreaking study has unveiled a novel genetic factor contributing to obesity, shedding light on the complex interplay between genetics and body weight regulation.
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© Clyde Campbell
Tsai Lab/ MIT Picower Institute
Irene Zorzan and Teresa Rayon, Babraham Institute
Chamberlain Lab