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Archive for category: Genetics

reelinTsai Lab/ MIT Picower Institute

New study sheds light on cellular vulnerabilities and resilience in Alzheimer’s disease

Alzheimer’s, brain, Genetics, Nature, Reelin, 24 July 2024/in dementia, E-News, Genetics, Neurology /by panglobal

A groundbreaking MIT study published in Nature offers new insights into the cellular mechanisms underlying Alzheimer’s disease, revealing potential targets for interventions to maintain cognitive function.  

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https://interhospi.com/wp-content/uploads/sites/3/2024/07/reelin.jpg 549 700 panglobal https://interhospi.com/wp-content/uploads/sites/3/2020/06/Component-6-–-1.png panglobal2024-07-24 17:05:592024-07-19 13:00:56New study sheds light on cellular vulnerabilities and resilience in Alzheimer’s disease
3. Human stem cell-based embryo model – Blastoids. Blue marks all nuclei, the green label marks cells of the inner cell mass, and the pink label is a readout of a ribosomal protein.Irene Zorzan and Teresa Rayon, Babraham Institute

New Code of Practice for stem cell-based embryo models addresses ethical concerns

Code of Practice, embryo models, ethics, Research, stem cell, 22 July 2024/in E-News, Genetics /by panglobal

Scientists in the UK have developed the first code of practice for research using stem cell-based embryo models, providing ethical guidelines and governance for this rapidly advancing field.  

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https://interhospi.com/wp-content/uploads/sites/3/2024/07/blastoid.png 1448 1448 panglobal https://interhospi.com/wp-content/uploads/sites/3/2020/06/Component-6-–-1.png panglobal2024-07-22 08:00:352024-07-16 14:35:03New Code of Practice for stem cell-based embryo models addresses ethical concerns
Jeffrey Chamberlain and Hichem TasfaoutChamberlain Lab

New gene therapy breakthrough offers hope for Duchenne muscular dystrophy patients

Duchenne muscular dystrophy, Genetics, Nature, treatment, 19 July 2024/in Congenital Diseases, E-News, Genetics /by panglobal

A groundbreaking gene therapy for Duchenne muscular dystrophy (DMD) has demonstrated significant potential in not only arresting muscle decline but also possibly repairing damaged muscle tissue. This novel treatment, developed by researchers at UW Medicine, utilises a series of protein packets delivered via viral vectors to replace the defective DMD gene within affected muscles.  

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https://interhospi.com/wp-content/uploads/sites/3/2024/07/Jeffrey-Chamberlain-left-and-Hichem-Tasfaout.jpg 426 640 panglobal https://interhospi.com/wp-content/uploads/sites/3/2020/06/Component-6-–-1.png panglobal2024-07-19 13:29:132024-07-19 13:29:13New gene therapy breakthrough offers hope for Duchenne muscular dystrophy patients
hearing loss

Genome editing restores hearing in mice with progressive hearing loss

CRISPR/Cas9, gene, hearing loss, 19 July 2024/in E-News, Genetics /by panglobal

Research from Mass Eye and Ear demonstrates successful use of CRISPR/Cas9 to target and disrupt a genetic mutation causing hearing loss, offering hope for future treatments in humans.  

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https://interhospi.com/wp-content/uploads/sites/3/2024/07/hearing_loss.jpg 974 1263 panglobal https://interhospi.com/wp-content/uploads/sites/3/2020/06/Component-6-–-1.png panglobal2024-07-19 08:00:592024-07-16 13:59:56Genome editing restores hearing in mice with progressive hearing loss
Dylan Taylor and Rajiv McCoy

Global gene expression study breaks European bias in genetic research

1000 Genomes Project, bias, diversity, Genetics, mutations, Nature, traits, 17 July 2024/in E-News, Genetics /by panglobal

New research from Johns Hopkins University expands our understanding of genetic variation across diverse populations, potentially improving the accuracy of genetic predictions and personalised medicine.  

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https://interhospi.com/wp-content/uploads/sites/3/2024/07/Dylan-Taylor-and-Rajiv-McCoy.jpg 467 700 panglobal https://interhospi.com/wp-content/uploads/sites/3/2020/06/Component-6-–-1.png panglobal2024-07-17 17:10:032024-07-16 12:33:19Global gene expression study breaks European bias in genetic research
cystic fibrosis treatment

Gene-editing breakthrough offers hope for cystic fibrosis treatment

Cystic fibrosis, gene-editing, lungs, pulmonology, 16 July 2024/in E-News, Genetics, Pulmonology /by panglobal

Researchers have developed a novel gene-editing approach that efficiently corrects the most common cystic fibrosis mutation, potentially paving the way for a one-time, permanent treatment with fewer side effects than current therapies.  

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https://interhospi.com/wp-content/uploads/sites/3/2024/07/Cystic-fibrosis.jpg 739 1682 panglobal https://interhospi.com/wp-content/uploads/sites/3/2020/06/Component-6-–-1.png panglobal2024-07-16 13:05:592024-07-16 13:05:59Gene-editing breakthrough offers hope for cystic fibrosis treatment
obesity

Genetic variant linked to obesity: New insights into SMIM1 gene’s role in metabolism

gene, obesity, SMIM1, study, Vel blood group, 25 June 2024/in E-News, Genetics /by panglobal

A groundbreaking study has unveiled a novel genetic factor contributing to obesity, shedding light on the complex interplay between genetics and body weight regulation.

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https://interhospi.com/wp-content/uploads/sites/3/2024/06/obesity_gene.jpg 1290 1935 panglobal https://interhospi.com/wp-content/uploads/sites/3/2020/06/Component-6-–-1.png panglobal2024-06-25 07:54:562024-06-25 07:54:56Genetic variant linked to obesity: New insights into SMIM1 gene’s role in metabolism
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