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Archive for category: Genetics

Genetic testing transforms care pathways for children with neurodevelopmental disorders

Genetic testing transforms care pathways for children with neurodevelopmental disorders

care pathway, Genetics, neurodevelopment, Paediatrics, 18 December 2024/in Adolescent Health, E-News, Genetics, Neurology, Paediatrics /by panglobal

UCLA Health study demonstrates significant impact of genetic diagnostics on treatment decisions and specialist referrals in complex neurodevelopmental cases, pointing towards more personalised medical approaches.  

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https://interhospi.com/wp-content/uploads/sites/3/2024/12/gene_children.jpg 739 1108 panglobal https://interhospi.com/wp-content/uploads/sites/3/2020/06/Component-6-–-1.png panglobal2024-12-18 13:10:402024-12-17 10:50:07Genetic testing transforms care pathways for children with neurodevelopmental disorders
gene therapy

New RNA technology enables gene therapy for previously untreatable muscular dystrophies

gene therapy, muscular dystrophy, RNA, 26 November 2024/in Congenital Diseases, E-News, Genetics /by panglobal

A groundbreaking RNA-based technology allows therapeutic genes that are too large for conventional delivery methods to be successfully transported into cells, offering new hope for treating muscular dystrophies and other genetic disorders caused by mutations in large genes.  

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https://interhospi.com/wp-content/uploads/sites/3/2024/11/gene_therapy.jpg 1357 1437 panglobal https://interhospi.com/wp-content/uploads/sites/3/2020/06/Component-6-–-1.png panglobal2024-11-26 08:00:102024-11-19 11:56:11New RNA technology enables gene therapy for previously untreatable muscular dystrophies
gout

Genetic bombshell shatters gout myths: Lifestyle choices not to blame, landmark study reveals

Genetics, gout, Research, 18 October 2024/in E-News, Genetics, Lifestyle Diseases, Research /by panglobal

New research challenges long-held beliefs about the causes of gout, highlighting the significant impact of genetics on the chronic inflammatory condition.  

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https://interhospi.com/wp-content/uploads/sites/3/2024/10/gout.jpg 641 961 panglobal https://interhospi.com/wp-content/uploads/sites/3/2020/06/Component-6-–-1.png panglobal2024-10-18 08:02:492024-10-18 12:58:27Genetic bombshell shatters gout myths: Lifestyle choices not to blame, landmark study reveals
blood stem cells© Clyde Campbell

Manipulating embryonic ‘biological clock’ could boost lab-grown blood stem cells

biological clock, regenerative medicine, stem cells, 20 September 2024/in E-News, Genetics, Regenerative Medicine /by panglobal

New research reveals how delaying inflammatory signalling can dramatically increase the number of blood stem cells formed during embryonic development, potentially aiding efforts to produce these cells in the laboratory.  

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https://interhospi.com/wp-content/uploads/sites/3/2024/09/stem_cells.png 508 1356 panglobal https://interhospi.com/wp-content/uploads/sites/3/2020/06/Component-6-–-1.png panglobal2024-09-20 08:00:382024-09-23 09:38:21Manipulating embryonic ‘biological clock’ could boost lab-grown blood stem cells
Tubercolosis

New genetic mutation linked to tuberculosis susceptibility challenges understanding of TNF’s role in immunity

gene, immune response, mutations, tuberculosis, tumour necrosis factor, 9 September 2024/in Communicable Diseases, E-News, Genetics /by panglobal

Researchers at The Rockefeller University have identified a rare genetic mutation that increases vulnerability to tuberculosis, potentially reshaping our understanding of tumour necrosis factor’s role in the immune system.  

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https://interhospi.com/wp-content/uploads/sites/3/2024/09/TB-lungs.jpg 800 748 panglobal https://interhospi.com/wp-content/uploads/sites/3/2020/06/Component-6-–-1.png panglobal2024-09-09 12:55:542024-09-09 12:55:54New genetic mutation linked to tuberculosis susceptibility challenges understanding of TNF’s role in immunity
reelinTsai Lab/ MIT Picower Institute

New study sheds light on cellular vulnerabilities and resilience in Alzheimer’s disease

Alzheimer’s, brain, Genetics, Nature, Reelin, 24 July 2024/in dementia, E-News, Genetics, Neurology /by panglobal

A groundbreaking MIT study published in Nature offers new insights into the cellular mechanisms underlying Alzheimer’s disease, revealing potential targets for interventions to maintain cognitive function.  

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https://interhospi.com/wp-content/uploads/sites/3/2024/07/reelin.jpg 549 700 panglobal https://interhospi.com/wp-content/uploads/sites/3/2020/06/Component-6-–-1.png panglobal2024-07-24 17:05:592024-07-19 13:00:56New study sheds light on cellular vulnerabilities and resilience in Alzheimer’s disease
3. Human stem cell-based embryo model – Blastoids. Blue marks all nuclei, the green label marks cells of the inner cell mass, and the pink label is a readout of a ribosomal protein.Irene Zorzan and Teresa Rayon, Babraham Institute

New Code of Practice for stem cell-based embryo models addresses ethical concerns

Code of Practice, embryo models, ethics, Research, stem cell, 22 July 2024/in E-News, Genetics /by panglobal

Scientists in the UK have developed the first code of practice for research using stem cell-based embryo models, providing ethical guidelines and governance for this rapidly advancing field.  

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https://interhospi.com/wp-content/uploads/sites/3/2024/07/blastoid.png 1448 1448 panglobal https://interhospi.com/wp-content/uploads/sites/3/2020/06/Component-6-–-1.png panglobal2024-07-22 08:00:352024-07-16 14:35:03New Code of Practice for stem cell-based embryo models addresses ethical concerns
Jeffrey Chamberlain and Hichem TasfaoutChamberlain Lab

New gene therapy breakthrough offers hope for Duchenne muscular dystrophy patients

Duchenne muscular dystrophy, Genetics, Nature, treatment, 19 July 2024/in Congenital Diseases, E-News, Genetics /by panglobal

A groundbreaking gene therapy for Duchenne muscular dystrophy (DMD) has demonstrated significant potential in not only arresting muscle decline but also possibly repairing damaged muscle tissue. This novel treatment, developed by researchers at UW Medicine, utilises a series of protein packets delivered via viral vectors to replace the defective DMD gene within affected muscles.  

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https://interhospi.com/wp-content/uploads/sites/3/2024/07/Jeffrey-Chamberlain-left-and-Hichem-Tasfaout.jpg 426 640 panglobal https://interhospi.com/wp-content/uploads/sites/3/2020/06/Component-6-–-1.png panglobal2024-07-19 13:29:132024-07-19 13:29:13New gene therapy breakthrough offers hope for Duchenne muscular dystrophy patients
hearing loss

Genome editing restores hearing in mice with progressive hearing loss

CRISPR/Cas9, gene, hearing loss, 19 July 2024/in E-News, Genetics /by panglobal

Research from Mass Eye and Ear demonstrates successful use of CRISPR/Cas9 to target and disrupt a genetic mutation causing hearing loss, offering hope for future treatments in humans.  

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https://interhospi.com/wp-content/uploads/sites/3/2024/07/hearing_loss.jpg 974 1263 panglobal https://interhospi.com/wp-content/uploads/sites/3/2020/06/Component-6-–-1.png panglobal2024-07-19 08:00:592024-07-16 13:59:56Genome editing restores hearing in mice with progressive hearing loss
Dylan Taylor and Rajiv McCoy

Global gene expression study breaks European bias in genetic research

1000 Genomes Project, bias, diversity, Genetics, mutations, Nature, traits, 17 July 2024/in E-News, Genetics /by panglobal

New research from Johns Hopkins University expands our understanding of genetic variation across diverse populations, potentially improving the accuracy of genetic predictions and personalised medicine.  

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https://interhospi.com/wp-content/uploads/sites/3/2024/07/Dylan-Taylor-and-Rajiv-McCoy.jpg 467 700 panglobal https://interhospi.com/wp-content/uploads/sites/3/2020/06/Component-6-–-1.png panglobal2024-07-17 17:10:032024-07-16 12:33:19Global gene expression study breaks European bias in genetic research
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