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Archive for category: Featured Articles

Featured Articles

Integrated solution takes radiologist closer to clinician?s therapeutic decision-making

, 26 August 2020/in Featured Articles /by 3wmedia

Radiologists at Belgium

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Prophylactic statins: yes or no?

, 26 August 2020/in Featured Articles /by 3wmedia

The many advances in cardiovascular diagnostic imaging technology, interventional procedures, drug development and elucidation of risk factors have resulted in a steady reduction in deaths from cardiovascular disease in most European countries. However CVD still remains the leading cause of mortality in Europe, with an annual toll of 4.3 million deaths, and experts predict that, with the ageing population as well as lifestyle changes that are increasing the prevalence of obesity and Type 2 diabetes, we are now facing a CVD epidemic that could overwhelm our health services.
Because of effective dissemination of information on CVD, people are increasingly aware of the modifiable risk factors, which include tobacco use and excessive alcohol consumption, a paucity of suitable exercise and a high fat and sugar diet. Many patients also know that statins, which reduce Low-Density Lipoprotein Cholesterol levels, can be taken for primary prevention of CVD; some even expect these drugs on demand. Indeed over 10% of UK residents now take statins, and The National Institute for Health and Care Excellence (NICE) is currently updating its guidelines to recommend statin therapy if the assessed risk of developing CVD within 10 years is 10% (the previous guidelines stated 20%). The American Heart Association and American College of Cardiology

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Digital breast tomosynthesis

, 26 August 2020/in Featured Articles /by 3wmedia

Worldwide breast cancer is the most common female cancer; in the West one in eight women eventually develop the disease. However the mortality rate has steadily decreased in recent decades, in large part due to improved screening programmes and earlier detection. The current gold standard screening tool is mammography, but in 2011 the FDA approved the first Digital Breast Tomosynthesis (DBT) system, and this or similar systems are now available in a limited number of Western hospitals, generating studies to compare the effectiveness of the two imaging modalities.
Healthcare professionals are cognizant with the limitations of mammography, particularly for imaging dense breasts. X-rays of each breast from different angles can only provide a 2D image of a 3D structure, and normal breast tissue can thus mask a tumour. In addition false positive results augment both patient anxiety and hospital workload. And patients are well aware (even if many male health professionals are not) that the compression necessary for allowing the whole breast to be adequately viewed during mammography is not merely

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New digital RVTM3 vacuum regulator

, 26 August 2020/in Featured Articles /by 3wmedia
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New frontiers in anesthesiology

, 26 August 2020/in Featured Articles /by 3wmedia

Anesthesiologists face a daunting task keeping up and adapting their practice to cope with the incessant advances in surgery, and to innovations within their own discipline.
Today

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A-Smart carts

, 26 August 2020/in Featured Articles /by 3wmedia
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OMNI (K)

, 26 August 2020/in Featured Articles /by 3wmedia
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How Schiller is redefining heart reate variability (HRV) analysis

, 26 August 2020/in Featured Articles /by 3wmedia
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CLEO

, 26 August 2020/in Featured Articles /by 3wmedia
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Molecular imaging: a prophetic means to investigate disease

, 26 August 2020/in Featured Articles /by 3wmedia

Medical researchers have long been fascinated by the possibility of studying molecular pathways inside a human being, in real time. This is now possible thanks to the new biomedical technology of molecular imaging.
The technology has its roots in nuclear medicine but also draws heavily on disciplines like molecular biology and cellular chemistry, medical physics, pharmacology and bioinformatics as well as traditional imaging techniques.

Deploying early warning weapons
Molecular imaging allows for the non-invasive visualization, characterization and quantification of cellular/sub-cellular targets and pathways in living subjects. Most distinctively, it allows for biological processes to be investigated and calibrated within their own environment, rather than through in-vitro or ex-vivo cell cultures in the laboratory.
As compared to more conventional imaging techniques, which are  based on measuring differences in target density, molecular imaging uses biomarker probes to produce chemical reactions/molecular changes in the target area, and thereby alter the image.
By studying the cells of a living subject in order to determine abnormalities which form the basis of disease, the proponents of molecular imaging say it can be deployed as a far more effective weapon than traditional imaging/pathology techniques for assessment, risk profiling, evaluation and follow-up. The latter are constrained to focus on the end- or late-stage effects of molecular alterations.

A door to personalized medical care

In effect, molecular imaging allows for diagnosis of major diseases, before the onset of traditional symptoms. It is therefore expected to have a major economic impact due to savings on the burden of managing and treating a disease at a later, more advanced stage.
Molecular imaging also opens the door to personalized medical care, by revealing the specific clinical biology of the disease process in a particular patient. This is especially relevant for major cardiovascular conditions such as atherosclerosis, thrombosis, ischemia and heart failure or transplant rejection. Molecular imaging holds invaluable potential in the fight against cancers, by being able to precisely diagnose and stage tumours, assess and monitor therapies and provide extremely accurate prognoses. It also promises to become a front-line weapon in the battle against degenerative neurological diseases such as Alzheimer

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