A bacterial toxin produced by certain strains of Escherichia coli may explain the alarming increase in colorectal cancer among young adults, according to groundbreaking research published in Nature. The study reveals that colibactin exposure in early childhood creates distinct genetic signatures that significantly increase cancer risk before age 50.
The European Medicines Agency has qualified the first artificial intelligence-based tool designed to evaluate liver biopsies in patients with metabolic dysfunction-associated steatohepatitis (MASH). The system, called AIM-NASH, helps pathologists assess disease severity and reduce variability in histological scoring, with the aim of accelerating drug development for this increasingly common liver condition.
New research reveals a rapid regenerative pathway activated minutes after liver injury through glutamate signalling between liver and bone marrow, offering potential therapeutic applications for liver damage.
A major new report by World Cancer Research Fund International provides strong evidence that following specific dietary and lifestyle patterns can significantly reduce cancer risk. The report, released 9 April, reviews 170 global studies and presents comprehensive recommendations based on patterns of eating, physical activity, and weight management rather than focusing on individual nutrients or […]
Korean researchers have developed a breakthrough gene therapy that restores vision loss caused by retinal degeneration. The therapy works by neutralising a protein called Prox1 that suppresses retinal regeneration. When the Prox1 protein is blocked, Müller glial cells in the retina can reprogram into stem-like cells that regenerate damaged neurons, restoring visual function.
The Cystic Fibrosis Foundation has committed up to US$2.3 million (about £1.7 million) in equity investment to Owlstone Medical for the development of a breath test to detect Pseudomonas aeruginosa (PA) infections in people with cystic fibrosis (CF). The Cambridge-based company announced the investment on March 25, 2025, marking a significant step forward in respiratory […]
Scientists have discovered two populations of stem cells in the retina with strong regenerative properties, according to a new study published in Science Translational Medicine. The research team identified human neural retinal stem-like cells (hNRSCs) that can differentiate into light-sensing cells, offering a potential source of stem cells for regenerative eye therapies.
University of Chicago researchers have developed a groundbreaking imaging technology that visualizes the spatial organization of genetic material in three dimensions, without relying on conventional optical instruments. This technique, called volumetric DNA microscopy, works by tagging DNA and RNA molecules and allowing neighboring tags to interact, creating a molecular network that encodes their relative positions […]
Groundbreaking research analysing over 40 million laboratory tests from more than 300,000 pregnancies has mapped detailed weekly changes across 76 different physiological parameters throughout pregnancy and postpartum. The study reveals that approximately half of the measured parameters take three months to a year to return to baseline levels after childbirth, highlighting the extensive physiological impact […]
Northwestern Medicine and Netherlands-based Vitestro have initiated a groundbreaking collaboration to validate the world’s first autonomous robotic phlebotomy device. The multi-centre clinical trial aims to address critical workforce shortages in laboratory medicine while improving sample quality, enhancing operational efficiency, and transforming the patient experience through advanced robotic technology.
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