Researchers at the University of Minnesota Twin Cities have demonstrated a groundbreaking process that combines 3D printing, stem cell biology, and lab-grown tissues for spinal cord injury recovery. The innovative approach uses microscopic channels to guide neural regeneration, offering new hope for treating complete spinal cord injuries.
Researchers have developed PathoPlex, a new multiplexed imaging technology capable of mapping over 140 proteins within cells at subcellular resolution. The framework identified kidney stress-related protein patterns in people with type 2 diabetes before clinical signs of disease appeared, potentially accelerating both diagnosis and treatment timelines.
Researchers have achieved a milestone in xenotransplantation by successfully transplanting a genetically modified pig lung into a brain-dead human recipient, where it remained viable and functional for nine days without hyperacute rejection or infection, according to research published in Nature Medicine.
A comprehensive investigation reveals sophisticated networks of editors, authors, and brokers systematically scamming the scientific publishing system at unprecedented scale. The research exposes coordinated fraud operations that have infiltrated major journals and publishers, with fraudulent publications growing exponentially faster than legitimate science.
OHSU scientists have developed OmicsTweezer, a powerful machine learning tool that uses advanced deep learning and optimal transport techniques to analyse cell type composition in human tissues. The breakthrough technology addresses long-standing batch effect challenges in cancer research, potentially improving therapeutic target identification and patient outcomes across multiple cancer types.
Researchers have developed a third-generation CRISPR technique that modifies gene expression by removing methylation marks rather than cutting DNA sequences. The approach uses catalytically dead Cas9 proteins fused to demethylating enzymes, offering a potentially safer alternative to conventional gene editing for treating inherited blood disorders including sickle cell disease and β-thalassemia.
In an interview, Dr Zheng-Yi Chen reveals how his team’s single-dose CRISPR therapy successfully restored hearing and balance in adult mice with DFNA41 genetic deafness, marking a potential breakthrough for treating progressive hearing loss in humans.
Washington University researchers have developed a quantitative technique measuring leg movement variability to accurately diagnose dystonia in paediatric cerebral palsy patients. The breakthrough identifies brain mechanisms underlying the condition, which could enable early intervention strategies to prevent this painful complication.
The International Hospital Federation has revealed finalists for its 2025 awards programme, with 81 healthcare organisations from 38 countries competing across eight categories. Winners will be announced at the World Hospital Congress in Geneva in November, recognising excellence in clinical quality, sustainability, and operational performance. A full list of finalists is listed below.
A comprehensive analysis spanning four years of global vaccination campaigns reveals that COVID-19 vaccines prevented 2.5 million deaths worldwide between 2020 and 2024. The landmark study, which examined vaccination impact across all age groups and pandemic phases, found that one life was saved for every 5,400 vaccine doses administered, with the vast majority of benefits […]
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McAlpine Research Group, University of Minnesota
OHSU/Christine Torres Hicks
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Matt Miller/ Washington University School of Medicine