Mayo Clinic researchers have developed BACDAC, a computational tool that exposes elusive genomic patterns in cancer samples with low DNA coverage, with the aim of transforming how clinicians predict tumour behaviour and guide personalised treatment decisions through enhanced detection of chromosomal instability markers.
China’s National Medical Products Administration has approved expanded production capacity for NEFECON®, the only etiological treatment for IgA nephropathy. The regulatory milestone addresses growing clinical demand across Asia, where over 5 million patients live with this progressive kidney disease requiring targeted therapeutic intervention.
A comprehensive global analysis of nearly 6,000 participants reveals that brief exposure to urban nature provides substantial mental health benefits, with urban forests emerging as particularly powerful environments for psychological wellbeing. The research offers evidence-based guidance for integrating green spaces into public health strategies.
The Gates Foundation announces unprecedented $2.5 billion investment through 2030 to accelerate research and development in chronically underfunded women’s health areas, targeting maternal, menstrual, gynaecological, and sexual health innovations for global impact, particularly in low- and middle-income countries.
Chinese researchers have developed a revolutionary hybrid microscope that simultaneously captures brain blood flow and neuronal activity across the entire mouse cortex with unprecedented detail. The LiTA-HM system achieves subcellular resolution over a 6mm field of view, opening new frontiers in neurovascular coupling research and brain-computer interface development.
A landmark multi-country study has uncovered compelling evidence that the majority of children and young adults clinically diagnosed with type 1 diabetes across sub-Saharan Africa actually have a previously unrecognised non-autoimmune form of insulin-deficient diabetes. The research fundamentally challenges current diabetes classification systems and could change treatment approaches for young people with diabetes in Africa […]
Artificial intelligence could unlock the full potential of therapeutic and assistive exoskeletons by enabling autonomous operation, reducing dependence on therapists and caregivers. However, researchers emphasise that richer patient data and more accurate digital twins are essential before these technologies can achieve widespread clinical deployment and revolutionise rehabilitation outcomes.
Researchers at the University of the Basque Country have developed a groundbreaking microfluidic device that efficiently extracts platelet-rich plasma (PRP) from whole blood using gravity sedimentation, achieving significantly lower platelet activation rates than conventional centrifugation methods whilst maintaining high purity levels.
Scientists have developed groundbreaking airway and alveolus chip models using induced pluripotent stem cells, revealing how SARS-CoV-2 and influenza trigger dramatically different immune responses in upper versus lower respiratory regions. The research offers new insights into COVID-19 pathology and potential therapeutic targets.
A large-scale prospective study across Australia and New Zealand has revealed that the internationally recognised Phoenix sepsis criteria identify fewer than 5% of children hospitalised with suspected sepsis, raising significant concerns about diagnostic accuracy and patient safety in paediatric emergency medicine.
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Ryuji Yokokawa, et. al. Kyoto University, Nature Biomedical Engineering https://doi.org/10.1038/s41551-025-01444-2 