An editorial in the Journal of Intensive Medicine questions the rigid 30 mL/kg fluid resuscitation guideline for septic shock patients, arguing that individualised treatment strategies based on patient-specific factors could improve outcomes whilst reducing risks associated with excessive fluid administration in this life-threatening emergency condition.
Researchers at the University of Macau and University of Hong Kong have developed an innovative multichamber capsule robot that selectively samples bodily fluids and delivers targeted medications via magnetic field control. This breakthrough addresses fundamental limitations in current capsule endoscopy by enabling integrated diagnosis and treatment through single oral administration.
Redefining prostate cancer diagnosis and care Bayer has outlined an ambitious new vision for transforming prostate cancer care globally, emphasizing innovation in imaging, early detection, and patient-centered treatment strategies. Presented ahead of the European Society for Medical Oncology (ESMO) 2025 Congress, the initiative reflects Bayer’s commitment to redefining standards in oncology and radiology through scientific […]
A wireless subretinal photovoltaic implant paired with augmented-reality glasses has enabled patients with complete central vision loss from geographic atrophy to read letters, numbers and words, according to results from a European clinical trial published in The New England Journal of Medicine on 20 October 2025.
An international research team has mapped distinct molecular “fingerprints” in blood proteins across 59 diseases, creating a comprehensive resource that could revolutionise how clinicians distinguish between different conditions and identify early warning signs of illness.
Researchers have developed a pioneering 3D bioceramic scaffold embedded with silver-gallium liquid metal nanoparticles that simultaneously prevents bacterial infections and promotes bone regeneration. The breakthrough technology offers a non-antibiotic solution to one of orthopaedic surgery’s most persistent challenges, with potential to transform outcomes for high-risk patients.
Scientists at the University of Cambridge have created three-dimensional embryo-like structures that produce blood stem cells through a naturally occurring developmental process, eliminating the need for supplementary growth factors. The innovation, termed ‘hematoids’, mimics human embryonic blood development and could transform approaches to regenerative medicine and disease modelling.
A tailored, multi-faceted intervention has achieved substantial reductions in wasteful pre-surgery testing across Michigan hospitals, demonstrating that education, teamwork and site-specific adaptation can eliminate low-value care whilst preserving patient safety. The RITE-Size programme reduced unnecessary testing rates from 68% to 40% over six months across three hospital settings.
Cambridge-based breath diagnostics specialist Owlstone Medical has been awarded up to $49.1 million by ARPA-H to develop at-home multi-cancer early detection tests. The POSEIDON programme aims to detect 30+ solid tumours at Stage I using synthetic biosensors analysed through breath and urine samples, addressing critical gaps in accessible cancer screening.
A landmark case published in the Journal of Hepatology describes the world’s first auxiliary liver xenotransplant from a genetically engineered pig to a living human recipient, with the patient surviving 171 days. The procedure demonstrates that genetically modified porcine livers can support essential hepatic functions in humans, whilst highlighting significant complications that must be addressed […]
April 2024
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Wellcome Collection via Creative Commons Search Repository
Parts of Figure c and d were produced using images from Smart Servier Medical Art (CC BY 4.0).
Moorfields Eye Hospital
Jitesh Neupane, University of Cambridge
© Journal of Hepatology / Zhang et al.