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Archive for category: E-News

E-News

Technique for rapidly killing bacteria using tiny gold disks and light

, 26 August 2020/in E-News /by 3wmedia

Researchers have developed a new technique for killing bacteria in seconds using highly porous gold nanodisks and light, according to a study. The method could one day help hospitals treat some common infections without using antibiotics, which could help reduce the risk of spreading antibiotics resistance.

‘We showed that all of the bacteria were killed pretty quickly . . . within 5 to 25 seconds. That’s a very fast process,’ said corresponding author Wei-Chuan Shih, a professor in the electrical and computer engineering department, University of Houston, Texas.

Scientists create gold nanoparticles in the lab by dissolving gold, reducing the metal into smaller and smaller disconnected pieces until the size must be measured in nanometers. Once miniaturized, the particles can be crafted into various shapes including rods, triangles or disks.

Previous research shows that gold nanoparticles absorb light strongly, converting the photons quickly into heat and reaching temperatures hot enough to destroy various types of nearby cells

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?Dry Eye? linked to chronic pain syndromes

, 26 August 2020/in E-News /by 3wmedia

University of Miami Miller School of Medicine researchers have found a link between

https://interhospi.com/wp-content/uploads/sites/3/2020/06/logo-footer.png 44 200 3wmedia https://interhospi.com/wp-content/uploads/sites/3/2020/06/Component-6-–-1.png 3wmedia2020-08-26 14:38:292020-08-26 14:38:46?Dry Eye? linked to chronic pain syndromes

Ultrasound sensors for improved breast cancer screening

, 26 August 2020/in E-News /by 3wmedia

The first prototype ultrasound sensors for a new improved breast screening technique have been developed as part of an Innovate UK funded collaboration between the National Physical Laboratory (NPL), University Hospitals Bristol (UHB), North Bristol NHS Trust (NBT), Precision Acoustics Ltd and Designworks. The team is now looking for commercial partners to translate the novel development into a clinical device.
NHS breast cancer screening in England is currently conducted using X-ray mammography, and further investigations may involve a clinical examination, more X-ray mammograms and conventional ultrasound.
During mammography, each breast is compressed between the two plates of an X-ray machine, which some women find very uncomfortable, and two X-rays are taken at different angles. However, the inability of 2D X-ray mammography to separate overlying tissue can lead to false positives and false negatives, and the hazards associated with ionizing radiation limit the frequency with which X-rays can be performed. Conventional ultrasound is highly operator-dependent and suffers from imaging problems, making cancerous tissue difficult to distinguish from healthy tissue.
NPL, UHB, NBT, Precision Acoustics and Designworks are developing a prototype clinical system for a new breast screening technique – using ultrasound computed tomography (UCT) – that may overcome the problems of diagnosing breast disease using conventional X-ray mammography and ultrasound scans. The new ultrasound method will be safer and lower cost than currently-used screening techniques, and the results should be easier for clinicians to interpret.
NPL has developed and patented a novel detection method employing pyroelectric sensors, which convert ultrasonic energy into heat, generating electrical signals which are eventually used to form the ultrasound image. These large-area thermal sensors should generate far fewer image artefacts than conventional piezoelectric detectors, which are sensitive to the phase of the arriving ultrasound waves.
In the new procedure, the patient

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Implantable device targets pancreatic cancer

, 26 August 2020/in E-News /by 3wmedia

Pancreatic cancer is the third leading cause of cancer deaths in the United States, in part because it is very difficult for chemotherapy drugs to reach the pancreas, which is located deep within the abdomen.

To help overcome that obstacle, researchers from MIT and Massachusetts General Hospital have now developed a small, implantable device that delivers chemotherapy drugs directly to pancreatic tumours. In a study of mice, they found that this approach was up to 12 times more effective than giving chemotherapy drugs by intravenous injection, which is how most pancreatic cancer patients are treated.

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Multi-faceted approach to diagnosing carpal tunnel syndrome

, 26 August 2020/in E-News /by 3wmedia

New guidelines approved by the American Academy of Orthopaedic Surgeons (AAOS) Board of Directors recommend the collective use of a thorough patient history and specific physical examination manoeuvres, in addition to observation and specific diagnostic tests to more definitively diagnose carpal tunnel syndrome (CTS), a common source of hand numbness and pain affecting approximately 3 million Americans

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Stem cell study paves way for therapies

, 26 August 2020/in E-News /by 3wmedia

Stem cells that have been specifically developed for use as clinical therapies are fit for use in patients, scientists have found.  The research focused on human embryonic stem cells.  It paves the way for clinical trials of cell therapies to treat conditions such as Parkinson

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Building a better concussion test

, 26 August 2020/in E-News /by 3wmedia

When athletes gets their bell rung on the field or court, there

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Optimal C-section rate may be as high as 19 percent to save lives of mothers and infants

, 26 August 2020/in E-News /by 3wmedia

The most commonly performed operation in the world is cesarean section, and rates of cesarean childbirth delivery vary widely from country to country, from as little as 2 percent to more than 50 percent of live births. The World Health Organization recommends countries not exceed 10 to 15 percent (10 to 15 C-section deliveries per 100 live births) for optimal maternal and neonatal outcomes.
However, new research examining the relationship between C-section rates and maternal and neonatal mortality in 194 countries concludes that as the country-level C-section rate increases up to 19 percent, maternal and neonatal mortality rates decline. C-section delivery rates above 19 percent showed no further improvement in maternal and neonatal mortality rates.
Researchers from Ariadne Labs, a joint centre of Brigham and Women

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Programmable electronic glasses provide digital lazy eye treatment

, 26 August 2020/in E-News /by 3wmedia

A new study on lazy eye found that programmable electronic glasses help improve vision in children just as well as the more traditional treatment using eye patches. This

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Triple-therapy patch delivers local treatment, prevents recurrence in colon cancer model

, 26 August 2020/in E-News /by 3wmedia

Investigators at Brigham and Women’s Hospital have developed a hydrogel patch that can adhere to tumours in a preclinical model of colon cancer, delivering a local, combination treatment as the elastic gel breaks down over time. The new technique may allow clinicians to someday use diagnostic colonoscopy equipment to immediately deliver treatment without the need for open surgery at a later date.

The researchers were able to deliver three therapeutic strategies in their mouse model of colon cancer: gene therapy, chemotherapy or thermal ablation or a combination of all three. The team used gold nanoparticles to deliver a gene therapy treatment that targets Kras, a known cancer gene, and used near-infrared radiation to release a chemotherapeutic and cause heat damage to the cancer cells. The local, triple-combination therapy not only shrank tumours but also had a sustained effect overtime, preventing tumour recurrence and significantly extending survival of mice.

The researchers examined the effects of the therapy both with and without resection (surgical removal of the tumour), which is the current standard treatment for colon cancer in humans. In human cases where resection is not possible, a neoadjuvant therapy, such as chemotherapy or radiation therapy, is often used to shrink tumours before clinicians attempt to remove them. Natalie Artzi, PhD senior author of the study and a principal investigator at BWH, and her colleagues anticipate that their hydrogel patch could someday be used to shrink tumours before resection or could eliminate the need for resection entirely. They plan to test the material in larger preclinical models and dive more deeply into the genetic changes resulting from therapy to pinpoint which genes are most critical to target.

Brigham and Women’s Hospital www.brighamandwomens.org/about_bwh/publicaffairs/news/pressreleases/PressRelease.aspx?PageID=2459

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