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Archive for category: E-News

E-News

Vaccination with GM2-KLH-QS21 does not improve outcome stage II melanomas patients in EORTC study

, 26 August 2020/in E-News /by 3wmedia

Results of an EORTC study show that vaccination with GM2/KLH-QS-21 does not benefit patients with stage II melanoma. Vaccination with GM2/KLH-QS-21 stimulates the production of antibodies to the GM2 ganglioside, an antigen expressed by many melanomas. Serological response to GM2 was shown to be a positive prognostic factor in patients with melanoma and was the rationale for this trial.

The idea of treating cancer with a vaccine has been around since the first vaccines against infectious disease were developed. The GM2 ganglioside, an antigen expressed in most melanomas but with limited expression in normal tissues, was thought to offer a suitable target for such therapeutic vaccination. Previous studies had shown that serological response against GM2 was a favourable prognostic factor. The five and ten year survival rates for patients with melanoma having primary tumours with a Breslow thickness greater than 1.5 mm are just of 74% and 61%, respectively, so EORTC trial 18961 was launched to compare vaccination to observation in these patients.

Prof. Alexander M.M. Eggermont of the Institut Gustave Roussy, Villejuif, Paris-Sud, and Universit

https://interhospi.com/wp-content/uploads/sites/3/2020/06/logo-footer.png 44 200 3wmedia https://interhospi.com/wp-content/uploads/sites/3/2020/06/Component-6-–-1.png 3wmedia2020-08-26 14:41:042020-08-26 14:41:24Vaccination with GM2-KLH-QS21 does not improve outcome stage II melanomas patients in EORTC study

Sedation before nerve block increases risks, not pain relief

, 26 August 2020/in E-News /by 3wmedia

New research suggests that sedating patients before a nerve block needed to diagnose or treat chronic pain increases costs, risks and unnecessary surgeries, and sedation does nothing to increase patient satisfaction or long-term pain control.
‘Sedation doesn

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Emerging technologies look deeper into the eyes to catch signs of disease

, 26 August 2020/in E-News /by 3wmedia

Since the 1960s, the gold standard test for viewing abnormal blood vessels in the eye has been fluorescein angiography. If an eye care professional detects signs of blood vessel abnormalities during a comprehensive dilated eye exam, this test is often the next step. Clinicians and researchers are especially interested in seeing blood vessels nearest to the retina, because those vessels may show early signs of distress in some diseases. But conventional fluorescein angiography isn

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Patients with poor nutritional status before bladder cancer operation have a higher risk of postoperative

, 26 August 2020/in E-News /by 3wmedia

Patients with bladder cancer are two times more likely to have complications after a radical cystectomy procedure if they have a biomarker for poor nutritional status before the operation, according to study findings presented last week at the 2013 Clinical Congress of the American College of Surgeons. Surgeons from the University of North Carolina at Chapel Hill School of Medicine and UNC Lineberger Comprehensive Cancer Center identified a potentially modifiable risk factor for such post-surgical problems: a low preoperative level of albumin, a marker of the protein level in the blood.

David C. Johnson, MD, MPH, lead author of the study and a senior urology resident at UNC School of Medicine, and colleagues evaluated the impact that patients

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Patients who are engaged in their own care are more likely to reduce the risk of future fractures

, 26 August 2020/in E-News /by 3wmedia

People over the age of 50 who have suffered a fracture because of a slip or trip play a central role in making sure they get proper care to prevent a future fracture, a new study has found.
 The findings are important because previous efforts to improve care for bone health after one of these fractures have had limited success.
Dr. Dorcas Beaton, lead author of the study and director of the Mobility Program Clinical Research Unit at St. Michael

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Neuroimaging study sheds light on cognitive fatigue in MS

, 26 August 2020/in E-News /by 3wmedia

A new study by Kessler Foundation scientists sheds light on the mechanisms underlying cognitive fatigue in individuals with multiple sclerosis. Cognitive fatigue is fatigue resulting from mental work rather than from physical labour. This study by Genova H et al: (

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Second Sight Medical Products? Argus II named Invention of the Year by Popular Science magazine

, 26 August 2020/in E-News /by 3wmedia

Second Sight Medical Products, Inc., the leading developer of retinal prostheses for the blind, is pleased to announce that its Argus II Retinal Prosthesis System (Argus II), has been recognised by Popular Science magazine as

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Quality of patient care drives physician satisfaction

, 26 August 2020/in E-News /by 3wmedia

Being able to provide high-quality health care is a primary driver of job satisfaction among physicians, and obstacles to quality patient care are a source of stress for doctors, according to a new RAND Corporation study.

While physicians note some advantages of electronic health records, physicians complain that the systems in use today are cumbersome to operate and are an important contributor to their dissatisfaction, the study found.

The findings suggest that the factors contributing to physician dissatisfaction could serve as early warnings of deeper quality problems developing in the health care system.

‘Many things affect physician professional satisfaction, but a common theme is that physicians describe feeling stressed and unhappy when they see barriers preventing them from providing quality care,’ said Dr. Mark Friedberg, the study’s lead author and a natural scientist at RAND, a non-profit research organisation. ‘If their perceptions about quality are correct, then solving these problems will be good for both patients and physicians.’

The findings are from a project, sponsored by the American Medical Association (AMA), designed to identify the factors that influence physicians’ professional satisfaction. The issue is of increasing importance as health reform and other forces in the U.S. health care system alter contemporary delivery and payment models.

‘Overcoming modern medicine’s greatest obstacles to first-rate medical care can simultaneously enhance the quality of care and improve professional satisfaction among physicians,’ said AMA President Dr. Ardis Dee Hoven. ‘The AMA is committed to leading a national dialog regarding the major factors driving many physicians to feel increasingly disconnected from what really matters

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Bone grafting improvements with the help of sea coral

, 26 August 2020/in E-News /by 3wmedia

Sea coral could soon be used more extensively in bone grafting procedures thanks to new research from Swansea University that has refined the material

https://interhospi.com/wp-content/uploads/sites/3/2020/06/logo-footer.png 44 200 3wmedia https://interhospi.com/wp-content/uploads/sites/3/2020/06/Component-6-–-1.png 3wmedia2020-08-26 14:41:042020-08-26 14:41:10Bone grafting improvements with the help of sea coral

Ultrasound device combined with clot-buster safe for stroke

, 26 August 2020/in E-News /by 3wmedia

A study led by researchers at The University of Texas Health Science Center at Houston (UTHealth) showed that a hands-free ultrasound device combined with a clot-busting drug was safe for ischemic stroke patients.

The results of the phase II pilot study were reported today in the American Heart Association journal Stroke. Lead author is Andrew D. Barreto, M.D., assistant professor of neurology in the Stroke Program at the UTHealth Medical School. Principal investigator is James C. Grotta, M.D., professor and chair of the Department of Neurology at the UTHealth Medical School, the Roy M. & Phyllis Gough Huffington Distinguished Chair and co-director of the Mischer Neuroscience Institute at Memorial Hermann-Texas Medical Center.

The device, which uses UTHealth technology licensed to Cerevast Therapeutics, Inc., is placed on the stroke patient

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