Breakthrough study shows anti-ageing gene reverses heart age

An anti-ageing gene discovered in a population of centenarians has been shown to rewind the heart’s biological age by 10 years. The breakthrough, published in Cardiovascular Research and led by scientists at the University of Bristol and the MultiMedica Group in Italy, offers a potential target for patients with heart failure.

1 Cattaneo M., Beltrami A.P., Thomas A., et. al. The longevity-associated BPIFB4 gene supports cardiac function and vascularization in aging cardiomyopathy, Cardiovascular Research, 2023;, cvad008. (open access). doi: