Korean researchers have developed a breakthrough gene therapy that restores vision loss caused by retinal degeneration. The therapy works by neutralising a protein called Prox1 that suppresses retinal regeneration. When the Prox1 protein is blocked, Müller glial cells in the retina can reprogram into stem-like cells that regenerate damaged neurons, restoring visual function.
Scientists have discovered two populations of stem cells in the retina with strong regenerative properties, according to a new study published in Science Translational Medicine. The research team identified human neural retinal stem-like cells (hNRSCs) that can differentiate into light-sensing cells, offering a potential source of stem cells for regenerative eye therapies.
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