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Tag Archive for: organoid

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Microglia integrated in human brain organoids respond to toxin-induced demyelination with morphological changes. Representative immunofluorescence images show microglia (IBA1, green) in a human brain organoid model. Panels show the response to control conditions, demyelination (induced by toxin), and remyelination, respectively. Magnified insets an the right highlight the detailed morphological changes of microglia in each condition.Lange et al., Sci. Trans. Med. 17, eadp7047 (2025)

Newly engineered human brain organoids reveal myelin production and repair processes

brain, myelin, organoid, 11 September 2025/in E-News, Neurology /by panglobal

Researchers have engineered sophisticated human brain organoids that faithfully model myelin production and repair processes. The groundbreaking model integrates immune cells called microglia, revealing their essential role in remyelination and providing a powerful new platform for testing potential multiple sclerosis therapies.

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https://interhospi.com/wp-content/uploads/sites/3/2025/09/myelination.jpeg 1000 756 panglobal https://interhospi.com/wp-content/uploads/sites/3/2020/06/Component-6-–-1.png panglobal2025-09-11 08:00:382025-09-08 13:59:15Newly engineered human brain organoids reveal myelin production and repair processes

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11 September 2025

Newly engineered human brain organoids reveal myelin production and repair processes

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