Neuroprosthetics breakthrough: brain implant enables real-time speech synthesis for ALS patient

Researchers at UC Davis have demonstrated the first brain-computer interface that directly translates neural activity into synthesised speech in real-time, allowing a man with severe ALS to communicate naturally with immediate audio feedback rather than text-based approaches.

Researchers identify how gut bacteria-specific immune cells breach the blood-brain barrier and trigger neuroinflammation through molecular mimicry, offering new therapeutic targets.

Gut bacteria immune cells attack brain in autoimmune discovery

Scientists have discovered a novel mechanism by which immune cells targeting gut bacteria can infiltrate the brain and cause neuroinflammation through molecular mimicry. The research reveals how intestinal inflammation promotes the migration of microbiota-specific T cells into the central nervous system, where they mistakenly attack brain proteins.

Brain

Brain theta waves link audiovisual speech and memory formation

Researchers have discovered that theta brain waves play a crucial role in integrating visual lip movements with speech sounds during memory formation. The study demonstrates how disrupting the natural synchronisation between these audiovisual cues affects neural oscillations in both the neocortex and hippocampus, potentially impacting speech memory accuracy.

Heart ageing could be reversible, breakthrough study reveals

Researchers at the National University of Singapore have developed a revolutionary biomaterial that demonstrates how environmental changes around heart cells could reverse age-related cardiac damage. The breakthrough research suggests that targeting the cellular environment, rather than the cells themselves, may offer new therapeutic pathways for heart rejuvenation.

gadoquatrane

Bayer submits low-dose gadolinium contrast agent for FDA approval

Bayer has submitted a New Drug Application to the US Food and Drug Administration for gadoquatrane, its investigational low-dose gadolinium-based contrast agent (GBCA) for contrast-enhanced magnetic resonance imaging of the central nervous system and other body regions. The submission covers use in adults and paediatric patients, including term neonates.

gadoquatrane

Bayer submits low-dose MRI contrast agent gadoquatrane for Japan approval

Bayer has submitted a groundbreaking marketing authorisation application to Japan’s Ministry of Health, Labour, and Welfare for gadoquatrane, an investigational contrast agent that could significantly improve MRI safety protocols. The macrocyclic agent delivers a remarkable 60% reduction in gadolinium exposure compared to standard-of-care agents, addressing critical concerns about cumulative gadolinium retention in patients requiring multiple […]

Roche Chest Pain Triage algorithm

Roche receives CE mark for chest pain triage algorithm

Roche has announced the CE marking of its innovative Chest Pain Triage algorithm, designed to enhance the detection of Acute Coronary Syndrome (ACS) in emergency departments. Developed in collaboration with Universitätsklinikum Heidelberg, this IVD medical device aims to transform cardiac care by providing standardised assessment tools for clinicians managing chest pain presentations.

diagnostics.ai

Diagnostics.ai launches first CE-IVDR transparent AI platform

Diagnostics.ai has launched what it claims is the industry’s first fully transparent machine learning platform for clinical real-time PCR diagnostics, achieving CE-IVDR certification as new European regulatory deadlines take effect. The PCR.AI platform represents a significant advancement in diagnostic AI transparency, demonstrating exactly how each result is achieved – a first for molecular testing machine […]

mystical patient encounters

Sacred connections: How meaningful patient encounters are rescuing exhausted physicians

A landmark survey in the United States has revealed that deeply meaningful patient encounters, termed “sacred moments,” could offer a powerful antidote to the epidemic of physician burnout plaguing healthcare systems worldwide.

Journal of Neuro Trauma

New brain injury framework replaces outdated classification system, transforms diagnosis and treatment

A revolutionary multidimensional framework for characterising acute traumatic brain injury is set to replace the outdated Glasgow Coma Scale-based classification system. The new Clinical, Biomarker, Imaging-Modifiers (CBI-M) approach integrates blood biomarkers, advanced neuroimaging, and patient-specific factors to provide clinicians with unprecedented diagnostic precision for the first 24 hours post-injury.