Researchers have developed a pioneering 3D bioceramic scaffold embedded with silver-gallium liquid metal nanoparticles that simultaneously prevents bacterial infections and promotes bone regeneration. The breakthrough technology offers a non-antibiotic solution to one of orthopaedic surgery’s most persistent challenges, with potential to transform outcomes for high-risk patients.
Researchers have identified GPR133/ADGRD1, a mechanosensitive adhesion G protein-coupled receptor, as a promising therapeutic target for osteoporosis. The receptor responds to both mechanical forces and molecular signals, enhancing bone formation through cAMP-dependent activation of β-catenin signalling. A novel small-molecule agonist significantly alleviated osteoporosis in preclinical models, suggesting potential for clinical development.
Scientists have engineered a portable 3D printing device that produces bone grafts directly onto fractures during surgery. The technology enables real-time fabrication of customised implants without pre-operative preparation, whilst incorporating antibiotics to prevent infection and promoting natural bone regeneration at the grafting site.
Tramstraat 15
5611CM Eindhoven
The Netherlands
+31 85064 55 82
info@interhospi.com
PanGlobal Media IS not responsible for any error or omission that might occur in the electronic display of product or company data.
Device / Jeon et al. 