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Archive for category: E-News

E-News

Simulation training improves critical decision-making skills of ER residents

, 26 August 2020/in E-News /by 3wmedia

A Henry Ford Hospital study found that simulation training improved the critical decision-making skills of medical residents performing actual resuscitations in the Emergency Department.
Researchers say the residents performed better in four key skill areas after receiving the simulation training: leadership, problem solving, situational awareness and communication. Their overall performance also sharpened.
While many studies have shown the benefits of simulation training for honing the skill level of medical professionals, Henry Ford

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Additional high blood pressure screening in developing countries would reduce cardiovascular disease

, 26 August 2020/in E-News /by 3wmedia

A 25 per cent increase in high blood pressure screening in 19 developing countries would reduce the number of cardiovascular disease (CVD) events and deaths that occur each year by up to 3 per cent in these countries. The preliminary data presented today at the World Congress of Cardiology are the first findings from a new report from Harvard that will be published later this year.
The study found that around 900 million people in developing countries have high blood pressure but that only one-third are aware of their disease. Moreover, only 100 million of these people receive treatment, while only 5 per cent of the total are controlled.
Against this backdrop, this study was designed to assess the cost-effectiveness of an intervention to increase screening by 25 per cent in developing countries using a non-lab screening tool to treat those with a systolic blood pressure of greater than 140 mmHg and CVD risk of greater than 20 per cent.
The study found that screening an additional 25 per cent of the population would lead to an increase of more than 10 per cent in the rate of appropriate treatment of hypertension in high-risk individuals. The intervention would lead to about a 1-3 per cent reduction in CVD events and deaths. Furthermore, the incremental cost-effectiveness ratios of these screening programs were found to be well below one times GDP per capita in the 19 developing countries assessed.
‘Strategies to increase the screening for hypertension could lead to significant reductions in CVD deaths, at costs that are considered to be acceptable according to WHO recommendations,’ said Dr. Thomas Gaziano, assistant professor, Harvard School of Medicine.
CVD is the world

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Minimally invasive treatment for ruptured aneurysm: Safe, reduces mortality

, 26 August 2020/in E-News /by 3wmedia

Emergency minimally invasive repair effectively treats potentially fatal ruptured aneurysms in the abdomen without major surgery, involves less recovery time and fewer discharges to in-patient care facilities
A burst aneurysm (a local area of bulge) in the abdominal aorta

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Injectable gel could repair tissue damaged by heart attack

, 26 August 2020/in E-News /by 3wmedia

University of California, San Diego researchers have developed a new injectable hydrogel that could be an effective and safe treatment for tissue damage caused by heart attacks.

The study was done by Karen Christman and colleagues Christman is a professor in the Department of Bioengineering at the UC San Diego Jacobs School of Engineering and has co-founded a company, Ventrix, Inc., to bring the gel to clinical trials within the next year.

Therapies like the hydrogel would be a welcome development, Christman explained, since there are an estimated 785,000 new heart attack cases in the United States each year, with no established treatment for repairing the resulting damage to cardiac tissue.

The hydrogel is made from cardiac connective tissue that is stripped of heart muscle cells through a cleansing process, freeze-dried and milled into powder form, and then liquefied into a fluid that can be easily injected into the heart. Once it hits body temperature, the liquid turns into a semi-solid, porous gel that encourages cells to repopulate areas of damaged cardiac tissue and to preserve heart function, according to Christman. The hydrogel forms a scaffold to repair the tissue and possibly provides biochemical signals that prevent further deterioration in the surrounding tissues.

‘It helps to promote a positive remodelling-type response, not a pro-inflammatory one in the damaged heart,’ Christman said.

What

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Software for analysing digital pathology images proving its usefulness

, 26 August 2020/in E-News /by 3wmedia

In a new study, a program known as Spatially Invariant Vector Quantisation (SIVQ) was able to separate malignancy from background tissue in digital slides of micropapillary urothelial carcinoma, a type of bladder cancer whose features can vary widely from case to case and that presents diagnostic challenges even for experts.
‘Being able to pick out cancer from background tissue is a key test for this type of software tool,’ says U-M informatics fellow Jason Hipp, M.D., Ph.D., who shares lead authorship of the paper with resident Steven Christopher Smith, M.D., Ph.D. ‘This is the type of validation that has to happen before digital pathology tools can be widely used in a clinical setting.’
To test the software

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Device may inject a variety of drugs without using needles

, 26 August 2020/in E-News /by 3wmedia

Getting a shot at the doctor

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First electronic retinas implanted in the UK

, 26 August 2020/in E-News /by 3wmedia

Surgeons in Oxford are the first in the UK to successfully implant an electronic retina into the back of an eye.
On 22 March 2012, Chris James became the first patient in the UK to receive this ground-breaking surgery as part of a clinical trial being carried out at John Radcliffe Hospital and King’s College Hospital in London.
Mr James’s operation took place at the Oxford Eye Hospital with the surgical team led by Professor Robert MacLaren.
He was assisted by Mr Tim Jackson, a consultant ophthalmic surgeon at King’s College Hospital in London.
The following week, a second patient, Robin Millar, a 60 year old music producer from London, received a retinal implant at King’s College Hospital, with Professor MacLaren assisting Mr Jackson.
Both patients were able to detect light immediately after the electronic retinas were switched on, and are now beginning to experience some restoration of useful vision. Further operations are now planned for other suitable patients.
The retinal implants have been developed by Retina Implant of Germany to restore some sight to people with retinitis pigmentosa, an inherited condition that affects around one in every 3,000 – 4,000 people in Europe.
Retinitis pigmentosa is a progressive disease that sees light-detecting cells in the retina deteriorate over time.
Retina Implant’s devices are designed to replace the lost cells in the retina. Patients have a small microchip containing 1,500 tiny electronic light detectors implanted below the retina. The optic nerve is able to pick up electronic signals from the microchip and patients can begin to regain some sight once more.
Professor MacLaren explains: ‘What makes this unique is that all functions of the retina are integrated into the chip. It has 1,500 light sensing diodes and small electrodes that stimulate the overlying nerves to create a pixellated image. Apart from a hearing aid-like device behind the ear, you would not know a patient had one implanted.’
Chris James, 54, a council worker from Wiltshire, first began to experience night blindness in his mid-20s and was diagnosed with retinitis pigmentosa following a referral to Oxford Eye Hospital.
For a number of years, Chris’ vision remained relatively stable. But in 1990, a large dip in his vision left him legally blind. In 2003, another decrease in vision rendered Chris completely blind in his left eye and only able to distinguish lights in his right.
After having the artificial retina implanted in his left eye, Chris can now recognise a plate on a table and other basic shapes. And his vision is continuing to improve as he learns to use the electronic chip in an eye that has been completely blind for over a decade.
The operation took eight hours and first required implantation of the power supply which is buried under the skin behind the ear, similar to a cochlear implant. This part of the operation was performed by Mr James Ramsden of Oxford University Hospitals assisted by Mr Markus Groppe, an academic clinical lecturer at the University of Oxford.
The electronic retina was then inserted into the back of the eye and stitched into position before being connected to the power supply.
Three weeks after the operation, Chris’ electronic retina was switched on for the first time. After some initial tuning and testing, Chris was able to distinguish light against a black background.
‘As soon as I had this flash in my eye, this confirmed that my optic nerves are functioning properly which is a really promising sign,’ Chris said. ‘It was like someone taking a photo with a flashbulb, a pulsating light, I recognised it instantly.’
Chris continues to have monthly follow-up testing of his microchip. In the meantime, he is testing the microchip at home. ‘It’s obviously early days but it’s encouraging that I am already able to detect light where previously this would have not been possible for me. I’m still getting used to the feedback the chip provides and it will take some time to make sense of this. Most of all, I’m really excited to be part of this research.’
Oxford Eye Hospital

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Robot computer programme: boosting memory of children who have survived head injury?

, 26 August 2020/in E-News /by 3wmedia

A research team from East Anglia, awarded a grant from children

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Second study investigates two-arm blood pressure difference

, 26 August 2020/in E-News /by 3wmedia

44 per cent of patients being treated for high blood pressure and who took part in the study either suffered vascular disease or died over a 10-year period
In January a research team from the Peninsula College of Medicine and Dentistry reported the first systematic review of findings related to the risk factors associated with a difference in blood pressure between arms.
The first study, which was published in The Lancet, suggested that a difference of more than 10mmHg or 15mmHg in systolic blood pressure (the

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Powering pacemakers with heartbeat vibrations

Cardiology, 26 August 2020/in E-News /by 3wmedia

Though pacemakers require only small amounts of energy (about 1 millionth of a Watt), their batteries have to be replaced periodically, which means multiple surgeries for patients. Researchers have searched for ways to prolong battery life — trying to generate energy to power a pacemaker using blood sugar, or the motion of the hands and legs — but these methods either interfere with metabolism or require a more drastic surgery, such as passing a wire from the limbs to the chest area.
Aerospace engineers M. Amin Karami and Daniel J. Inman, from the University of Michigan in Ann Arbor, have developed a prototype device that could power a pacemaker using a source that is surprisingly close to the heart of the matter: vibrations in the chest cavity that are due mainly to heartbeats.
In their method, vibrations in the chest cavity deform a layer of piezoelectric material, which is able to convert mechanical stress into electrical current. Tests indicate that the device could perform at heart rates from 7 to 700 beats per minute (well below and above the normal range), and that it could deliver eight times the energy required for a pacemaker. Furthermore, the authors write, the amount of energy generated is always larger than the amount required to run a pacemaker, regardless of heart rate.
Though the team has yet to develop a prototype that is biocompatible, they say that the potential to package this energy harvester with pacemakers gives it an advantage over competing methods.
U-M Department of Aerospace Engineering

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