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Archive for category: E-News

E-News

Oxford COVID-19 policy ‘Supertracker’ wins support from OECD, World Bank

, 26 August 2020/in Corona News, E-News /by 3wmedia

Oxford has launched the ‘Oxford Supertracker’ < https://supertracker.spi.ox.ac.uk > – a global directory for COVID-19 policy trackers and surveys – to enable policy-makers and stakeholders to follow and evaluate policy changes and their impact on the COVID-19 pandemic in the UK, Europe and around the world.
Marek Naczyk, Oxford Associate Professor in Comparative Social Policy and project lead, said: “As social scientists and concerned citizens, we felt compelled to work on this tool to ensure policy-makers and the public can access information on policy measures in the wake of COVID-19. We have been encouraged by the interest to date from many international organisations, including OECD and the World Bank, highlighting how the Department of Social Policy’s interdisciplinary background is well placed for the continued development of the tool. Our ambition is for the Oxford ‘Supertracker’ to be the go-to portal sharing all known policy-related data sources in one place.”
Numerous organisations have produced trackers to allow policy-makers and stakeholders to follow and evaluate policy changes and their impact on the pandemic. The Oxford Supertracker project makes this information freely available with one tool, allowing users to search and identify international policy.
Sebastian Königs and Andrea Garnero, Economists at The Organisation for Economic Co-operation and Development (OECD) said: “The team behind the Oxford Supertracker have done an impressive job in assembling the rapidly growing data on countries’ COVID responses and in making them readily available and easily searchable. This is an enormous service to the research and policy community, including many here at the OECD.”
Ugo Gentilini, Global Lead for Social Assistance at the World Bank, commented on the Supertracker, saying: “The Oxford Supertracker offers a precious compass to help policy-makers, practitioners and researchers to navigate the rich and evolving set of trackers available globally.”
The COVID-19 policy tracker started in March as a Twitter thread by Oxford DPhil student Lukas Lehner. But it has evolved into the Supertracker, a comprehensive global directory of more than 100 data sources.
Compiling policy trackers and surveys, the Supertracker allows users to search by:

  • Policy area – such as ‘education’ or ‘social and economic’
  • Country coverage
  • Data format, and
  • Author.

It will be updated with input from policy-makers, researchers and users, to identify symmetries and gaps in existing trackers and propose concrete actions to address these. These will be particularly relevant to the social policy and economic inequality prevention measures, that are put in place as lockdown policies ease.
Visit the Oxford Supertracker here: https://supertracker.spi.ox.ac.uk A data summary can be downloaded as a CSV for offline analysis.

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Pan-European consortium established to rapidly develop vaccine

, 26 August 2020/in Corona News, E-News /by 3wmedia

A pan-European consortium of biotech companies announced April 23 that they will collaborate to develop and manufacture on a large scale a novel adenoviral vector-based vaccine against COVID-19.
The vaccine candidate is expected to enter clinical trials mid 2020 with vaccine production planned to start following the successful trials. If all goes according to plan, approximately 6 million doses of the vaccine are expected to be available early in 2021.
The consortium comprises Italian company ReiThera, German LEUKOCARE, and Belgian Univercells. They provide expertise in vector-based vaccine development, vaccine formulation and manufacturing, respectively. Their combined expertise is expected to enable efficient and ultra-fast vaccine development.
The vaccine technology is based on a novel, ReiThera-proprietary simian adenoviral vector with strong immunological potency and low pre-existing immunity in humans. Vaccines based on simian adenoviral vectors have been extensively evaluated in Phase 1 and 2 clinical trials and proved to be safe and immunogenic. ReiThera is currently preparing for a COVID-19 first-in-human trial to be started in Italy in mid 2020.
In parallel to its clinical development, the consortium will start manufacturing and stockpiling the vaccine. With these pilot scale processes, approximately 6 million doses of the vaccine are expected to be available early in 2021. Based on the Phase 1/2 clinical results and a path agreed with regulatory authorities, the intention with these doses will be to vaccinate the most exposed people such as medical and healthcare professionals and highly vulnerable individuals.
LEUKOCARE will contribute to the drug product development by developing a highly stable liquid vaccine formulation based on its well-established technology platform for formulations of viruses and viral vectors.
Univercells will take advantage of the previous successes of its scale-X bioreactor and NevoLine biomanufacturing platform to adapt and scale-up the technology platform and enable the mass production of ReiThera’s vaccine candidate.
Michael Scholl, Chief Executive Officer of LEUKOCARE, commented: “By combining the experience of the partners, the advanced stages of this vaccine development will allow for a swift response to the COVID-19 pandemic. Facing the current challenges, our approach for the fast and low-risk development of drug products with superior stability characteristics is even more important regarding timelines and social impact.”

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The 43rd World Hospital Congress rallies for people-centered health services in times of peace and crisis

, 26 August 2020/in E-News /by 3wmedia

Hosted by the Ministry of Health of the Sultanate of Oman, the 43rd World Hospital Congress of the International Hospital Federation (IHF) will go over some of the most pressing subjects in the global healthcare community in over 40 sessions lined up for discussion on 6 to 9 November in Muscat.
In between times of peace, situations of humanitarian crisis always manage to creep in or sweep off the guards of healthcare systems and even governments. Epidemics, wars and terrorist attacks, natural disasters and man-made hazards, and major cases of poverty and famine often fall on the ground wrecking communities’ health defenses. The persistence of these phenomena and their prevailing nature demand collective attention and actionable long-lasting mitigation plans, which are best formulated with resilient health services, health investments for prosperity, and innovations for health impact.
Under an overarching theme “People at the heart of health services in peace and crisis”, the agenda of the World Hospital Congress will cover the stages of preparation while in peace, action when in crisis and moving forward to better healthcare services for communities.
The World Health Organization (WHO) will be hosting an opening keynote session on the role of hospitals in support of universal health coverage to be presented by Dr. Edward Kelley, Director of the Department of Integrated Health Services of WHO. It will be followed by a ministerial-level panel discussion to further explore how hospitals are integral to the UHC and PHC agenda and how they can contribute to transforming health systems.
In another keynote presentation, Dr. Akihiro Seita, Director of Health Programme of UNRWA (UN Relief and Works Agency for Palestine refugees in the Near East) will share about the challenge of UNRWA in providing Palestine refugees access to hospital services. In succeeding sessions, stories and perspectives taken right from the terrorist attacks in Kenya and the continuing displacement and refugee casualties in Afghanistan are ready to open many eyes to the bigger fights of the healthcare community against massive violence.
A number of sessions are equally dedicated to reviewing the central role of hospitals in the health system. In a keynote session, Dr. Agnès Soucat, Director of Health Systems Governance and Financing at WHO will help delegates further understand the role of hospitals and health services affecting population well-being. Likewise, Dr. Melinda Estes, President and Chief Executive Officer of the Saint Luke’s Health System in USA will share her knowledge about how hospitals and health systems can drive community health and prosperity.
Inspiring accounts about the birth of the Oman Cancer Association, an Omani community built from the sentiments of a cancer survivor now collaborating with several programs supportive of cancer patients, will also be told by Hon. Yuthar Mohammed Al Rawahy, Founder and Honorary Life President of the Oman Cancer Association. More sessions from this year’s congress host – the Ministry of Health of the Sultanate of Oman – will share about Oman’s stories of resilience, the integrated healthcare system they have established, as well as e-health innovations and achievements.
Innovation pathways will also take the floor in a keynote presentation to be delivered by Sir Andrew Dillon CBE, Chief Executive of the National Institute for Health and Care Excellence in UK.
More topics on health innovations will be tackled in detail through the inspiring digital transformation experience of Catalonia and the huge success of Taiwan’s healthcare IT transformation.
GS1 Healthcare has also arranged a session to share examples from several countries of enhanced healthcare results by the introduction of global standards, starting at procurement in healthcare organizations.
The concept of ‘anchor institutions’ will be elaborated by senior health service leaders and experts from the NHS Confederation.
Composed of several more currently relevant topics, the agenda of the Congress will once again serve eye-opener stories happening around the globe posting both serious challenges and ripe potentials to innovate and invest on people-centered health services whether in peace or in crisis.
The IHF Muscat World Hospital Congress will take place through four consecutive days of knowledge harvest including pre-Congress sessions on ‘Economics for Healthcare Leaders’ and ‘The “Fast Forward” Initiative for community- and person-centered hospitals and health services’. This annual event will close with a hospital tour to The Royal Hospital and the Sultan Qaboos University Hospital. https://worldhospitalcongress.org/

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Stanford researchers create a wireless, battery-free, biodegradable blood flow sensor

, 26 August 2020/in E-News /by 3wmedia

A new device developed by Stanford University researchers could make it easier for doctors to monitor the success of blood vessel surgery. The sensor monitors the flow of blood through an artery. It is biodegradable, battery-free and wireless, so it is compact and doesn’t need to be removed and it can warn a patient’s doctor if there is a blockage.
“Measurement of blood flow is critical in many medical specialties, so a wireless biodegradable sensor could impact multiple fields including vascular, transplant, reconstructive and cardiac surgery,” said Paige Fox, assistant professor of surgery and co-senior author of the paper.
Monitoring the success of surgery on blood vessels is challenging as the first sign of trouble often comes too late. By that time, the patient often needs additional surgery that carries risks similar to the original procedure. This new sensor could let doctors keep tabs on a healing vessel from afar, creating opportunities for earlier interventions.
The sensor wraps snugly around the healing vessel, where blood pulsing past pushes on its inner surface. As the shape of that surface changes, it alters the sensor’s capacity to store electric charge, which doctors can detect remotely from a device located near the skin but outside the body. That device solicits a reading by pinging the antenna of the sensor, similar to an ID card scanner. In the future, this device could come in the form of a stick-on patch or be integrated into other technology, like a wearable device or smartphone.
The researchers first tested the sensor in an artificial setting where they pumped air through an artery-sized tube to mimic pulsing blood flow. Surgeon Yukitoshi Kaizawa, a former postdoctoral scholar at Stanford and co-author of the paper, also implanted the sensor around an artery in a rat. Even at such a small scale, the sensor successfully reported blood flow to the wireless reader. At this point, they were only interested in detecting complete blockages, but they did see indications that future versions of this sensor could identify finer fluctuations of blood flow.
Stanford University https://tinyurl.com/y6g4qmng

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European Commission raises €15.9 billion for Coronavirus Global Response

, 26 August 2020/in E-News /by 3wmedia

The ‘Global Goal: Unite for our Future’ pledging summit organised 27 June by the European Commission and Global Citizen mobilised €6.15 billion in additional funding to help develop and ensure equitable access to coronavirus vaccines, tests and treatments. This brings total pledges under the Coronavirus Global Response pledging marathon, launched by European Commission President Ursula von der Leyen on 4 May, to €15.9 billion. The money raised will also support economic recovery in the world’s most fragile regions and communities..
The latest pledging session includes a €4.9 billion pledge by the European Investment Bank, in partnership with the European Commission, and €485 million committed by EU Member States.
Forty governments took part in the summit and committed to ensuring universal access to coronavirus medicines. They also vowed to help rebuild communities that have been hit hard by the pandemic, in a fair and just way.
As a landmark of global solidarity, the summit resulted in commitments for the production capacity of over 250 million vaccine doses for middle and lower income countries.
“The world will only be freed from this pandemic when vaccines, tests and treatments are available and affordable to everyone who needs them. Today’s pledges and Europe’s contribution bring us closer to this global goal. Europe is in this for the long haul. We will use all of our convening power for the common good. There is a strong alliance out there to beat this virus, together.” Von der Leyen said.
The European Investment Bank is building a pipeline of investment projects to develop and scale up production of coronavirus vaccines, tests and treatments, in partnership with the European Commission, the World Health Organization and the Coalition for Epidemic Preparedness Innovations (CEPI).
In recent weeks, the EIB announced a new Memorandum of Understanding with the WHO, an Advisory agreement with CEPI, a collaboration with the Israel Innovation Authority and a €50 million financing agreement with Pluristem to develop therapies for coronavirus vaccine development finance for BioNTech and increased cooperation with UN-Habitat.

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Italian doctors call on world to change perspective on care

, 26 August 2020/in Corona News, E-News /by 3wmedia

Doctors at the epicentre of the COVID-19 outbreak in Italy have made an urgent call on the rest of the world to change the way they treat pandemic patients. In a paper published in NEJM Catalyst (21 March 2020) they say patient-centred care is no longer feasible in a pandemic and that ‘community-centred’ care should be the new norm.
They say that hospitals might be the main COVID-19 carriers as they are rapidly filled with infected patients.
“This disaster could be averted only by massive deployment of outreach services,” they emphasize.
The doctors (Nacoti M, et al – At the Epicenter of the Covid-19 Pandemic and Humanitarian Crises in Italy: Changing Perspectives on Preparation and Mitigation) who work at Papa Giovanni XXIII Hospital in Bergamo, a brand-new state-of-the-art facility with 48 intensive-care beds, say: “Our own hospital is highly contaminated, and we are far beyond the tipping point: 300 beds out of 900 are occupied by Covid-19 patients. Fully 70% of ICU beds in our hospital are reserved for critically ill Covid-19 patients with a reasonable chance to survive. The situation here is dismal as we operate well below our normal standard of care. Wait times for an intensive care bed are hours long. Older patients are not being resuscitated and die alone without appropriate palliative care, while the family is notified over the phone, often by a well-intentioned, exhausted, and emotionally depleted physician with no prior contact.
“But the situation in the surrounding area is even worse. Most hospitals are overcrowded, nearing collapse while medications, mechanical ventilators, oxygen, and personal protective equipment are not available. Patients lay on floor mattresses. The health care system struggles to deliver regular services — even pregnancy care and child delivery — while cemeteries are overwhelmed, which will create another public health problem.
They say pandemic solutions are required for the entire population, not only for hospitals.

  1. Home care and mobile clinics avoid unnecessary movements and release pressure from hospitals.
  2. Early oxygen therapy, pulse oximeters, and nutrition can be delivered to the homes of mildly ill and convalescent patients, setting up a broad surveillance system with adequate isolation and leveraging innovative telemedicine instruments.

https://catalyst.nejm.org/doi/full/10.1056/CAT.20.0080

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IHF Congress will convene health leaders from around the globe in Oman

, 26 August 2020/in E-News /by 3wmedia

Health leaders and professionals from more than 40 countries will be in Oman on 6-9 November for the 43rd World Hospital Congress of the International Hospital Federation for in-depth discussions on people-centered health services in times of peace and crisis. The scientific sessions will bring up actionable ideas on how health services can be resilient to various issues, supported by investments contributing to the prosperity of the country and innovative to increase health gain.
IHF’s annual Congress, hosted this year by the Ministry of Health of the Sultanate of Oman, will showcase a comprehensive event experience with:

  • 150 notable Speakers who will present advancements and share best practices in leadership, management and service delivery;
  • 40 Sessions that will delve into various dimensions of resilience, contribution of the health industry to prosperity and impactful innovations;
  • Poster display of best practices from different hospitals and organizations;
  • Solid networking opportunity enhanced by a new mobile application – CERCA – for secure and privacy-protected network-building activity; 
  • Two intensive Pre-conference sessions: Economics for Health Leaders and The “Fast Forward” Initiative for Community- and Person-Centered Hospitals and Health Services;
  • 2019 IHF Awards where outstanding initiatives will be recognized;
  • A friendly exhibition environment to make new connections or reunite with peers;
  • Hospital Site Visits to The Royal Hospital and Sultan Qaboos University Hospital, of which funds collected will be donated to St. Gemma’s Hospice in Leeds, a charity supported by a life-changing campaign called #hellomynameis.


The World Hospital Congress is a one-stop shop for the healthcare professional seeking the opportunity and environment in which to engage in a 360-degree learning and knowledge-sharing experience among peers. http://worldhospitalcongress.org

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On the frontline

, 26 August 2020/in E-News /by 3wmedia
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More than 9 in 10 surgeons encounter a needlestick injury

, 26 August 2020/in E-News /by 3wmedia

95% of surgeons have either been personally affected by a needlestick injury or have seen a colleague experience one, a new global survey has found, increasing their risk of infection. The survey – the first of its kind undertaken – was conducted by SERMO for Mölnlycke, a wound care and surgical products company.
The survey looked at key opinions from 510 surgeons across six countries relating to infection prevention and the role of high-quality gloves in improving patient and clinician safety. In particular, it demonstrated the importance that surgeons place on high quality gloves in the fight against needlestick injuries and exposure to blood-borne viruses, like HIV.

An estimated two million needlestick injuries occur among health workers each year, resulting in increased exposure to HIV, Hepatitis C
and other blood-borne viruses. Needlestick injuries occur when a needle or other sharp instrument accidentally penetrates the skin, yet the underreporting to occupational health departments is well established.

The survey revealed that 93% of surgeons think that high quality gloves reduce the chance of exposure to blood-borne viruses and 83% said that the quality of gloves affects their sense of being protected from needlestick injuries.

On the topic of patient safety, 81% of surgeons believe that high quality gloves impact overall patient outcomes and 89% agreed that high quality gloves improve patient safety in the operating theatre. When asked about glove failure during an operation, 78% of surgeons responded that it increases the risk of surgical site infections.

Commenting on the survey findings, John Timmons, Clinical Staff Nurse and Internatio-
nal Medical Director, said: “Each year, millions of surgeons and their teams risk exposure to life threatening blood-borne viruses and this ground-breaking survey highlights the value that surgeons across the globe place on high quality gloves. Surgeons clearly recognise their role in both ensuring the safety of surgeons and improving outcomes for patients.

“Surgical gloves are one of the key factors that prevent infections in the operating room and should not be viewed as a commodity. High quality means fewer glove failures, yet we are increasingly seeing healthcare systems around the world prioritise price over quality.”

Healthcare-associated infections (HAIs) are the most frequent adverse event in healthcare delivery worldwide. Hundreds of millions of patients are affected by HAIs worldwide each year, leading to significant mortality rates. Of every 100 hospitalized patients at any given time, an estimated seven patients in developed countries will acquire at least one HAI. www.molnlycke.com/biogel/

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Tiny generators turn body motion into weight control and wound-healing therapies

, 26 August 2020/in E-News /by 3wmedia

Although electrical stimulation has therapeutic potential for various disorders and conditions, ungainly power sources have hampered practical applications. Now bioengineers have developed implantable and wearable nanogenerators from special materials that create electrical pulses when compressed by body motions. The pulses controlled weight gain and enhanced healing of skin wounds in rat models.
The work was performed by a research team led by Xudong Wang, Ph.D., Professor of Material Sciences and Engineering, College of Engineering, University of Wisconsin-Madison, and supported by the National Institute of Biomedical Imaging and Bioengineering (NIBIB).
The researchers used what are known as piezoelectric and dielectric materials, including ceramics and crystals, which have a special property of creating an electrical charge in response to mechanical stress.
“Wang and colleagues have engineered solutions to a number of technical hurdles to create piezoelectric and dielectric materials that are compatible with body tissues and can generate a reliable, self-sufficient power supply. Their meticulous work has enabled a simple and elegant technology that offers the possibility of developing electrical stimulation therapies for a number of major diseases that currently lack adequate treatments,” explained David Rampulla, Ph.D., director of the Program in Biomaterials and Biomolecular Constructs at NIBIB.
Worldwide, more than 700 million people — over 100 million of them children — are obese, causing health problems such as cardiovascular disease, diabetes, kidney disease, and certain cancers. In 2015 approximately four million people died of obesity-related causes.
To address this crisis, Wang and his colleagues developed a vagal nerve stimulator (VNS) that dramatically improves appetite suppression through electrical stimulation of the vagus nerve. The approach is a promising one that has previously not proven practical because patients must carry bulky battery packs that require proper programming, and frequent recharging.
The VNS consists of a small patch, about the size of a fingernail, which carries tiny devices called nanogenerators. Minimally invasive surgery was used to attach the VNS to the stomachs of rats. The rat’s stomach movements resulted in the delivery of gentle electrical pulses to the vagus nerve, which links the brain to the stomach. With the VNS, when the stomach moved in response to eating, the electric signal told the brain that the stomach was full, even if only a small amount of food was consumed.
The device curbed the rat’s appetite and reduced body weight by a remarkable 40 percent. “The stimulation is a natural response to regulate food intake, so there are no unwanted side effects,” explained Wang. When the device was removed the rats resumed their normal eating patterns and their weight returned to pre-treatment levels.
“Given the simplicity and effectiveness of the system, coupled with the fact that the effect is reversible and carries no side-effects, we are now planning testing in larger animals with the hope of eventually moving into human trials,” said Wang.
In another NIBIB-funded study in a rat experimental model, the researchers used their nanogenerator technology to determine whether electrical stimulation would accelerate healing of wounds on the skin surface.
For this experiment, a band of nanogenerators was placed around the rat’s chest, where the expansion from breathing created a mild electric field. Small electrodes in a bandage-like device were placed over skin wounds on the rat’s back, where they directed the electric field to cover the wound area.
The technique reduced healing times to just three days compared with nearly two weeks for the normal healing process.
Similar to the case with appetite suppression, it was known that electricity could enhance wound healing, but the devices that had been developed were large and impractical. The nanogenerator-powered bandage is completely non-invasive and produced a mild electric field that is similar to electrical activity detected in the normal wound-healing process.
The researchers observed electrical activation of normal cellular healing processes that included the movement of healthy skin fibroblasts into the wound, accompanied by the release of biochemical factors that promote the growth of the fibroblasts and other cell types that expand to repair the wound space.
“The dramatic decrease in healing time was surprising,” said Wang, “We now plan to test the device on pigs because their skin is very similar to humans.”
The team believes the simplicity of the electric bandage will help move the technology to human trials quickly. In addition, Wang explained that the fabrication of the device is very inexpensive and a product for human use would cost about the same as a normal bandage.
NIBIB https://tinyurl.com/y3cxut6p

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