Pancreatic cancer is the third leading cause of cancer deaths in the United States, in part because it is very difficult for chemotherapy drugs to reach the pancreas, which is located deep within the abdomen.

To help overcome that obstacle, researchers from MIT and Massachusetts General Hospital have now developed a small, implantable device that delivers chemotherapy drugs directly to pancreatic tumours. In a study of mice, they found that this approach was up to 12 times more effective than giving chemotherapy drugs by intravenous injection, which is how most pancreatic cancer patients are treated.

Stem cells that have been specifically developed for use as clinical therapies are fit for use in patients, scientists have found.  The research focused on human embryonic stem cells.  It paves the way for clinical trials of cell therapies to treat conditions such as Parkinson

The most commonly performed operation in the world is cesarean section, and rates of cesarean childbirth delivery vary widely from country to country, from as little as 2 percent to more than 50 percent of live births. The World Health Organization recommends countries not exceed 10 to 15 percent (10 to 15 C-section deliveries per 100 live births) for optimal maternal and neonatal outcomes.
However, new research examining the relationship between C-section rates and maternal and neonatal mortality in 194 countries concludes that as the country-level C-section rate increases up to 19 percent, maternal and neonatal mortality rates decline. C-section delivery rates above 19 percent showed no further improvement in maternal and neonatal mortality rates.
Researchers from Ariadne Labs, a joint centre of Brigham and Women

Physicists from the University of Sydney have devised a way to use diamonds to identify cancerous tumours before they become life threatening.
Their reveal how a nano-scale, synthetic version of the precious gem can light up early-stage cancers in non-toxic, non-invasive Magnetic Resonance Imaging (MRI) scans.
Targeting cancers with tailored chemicals is not new but scientists struggle to detect where these chemicals go since, short of a biopsy, there are few ways to see if a treatment has been taken-up by a cancer.
Led by Professor David Reilly from the School of Physics, researchers from the University investigated how nanoscale diamonds could help identify cancers in their earliest stages.
‘We knew nano diamonds were of interest for delivering drugs during chemotherapy because they are largely non-toxic and non-reactive,’ says Professor Reilly.
‘We thought we could build on these non-toxic properties realizing that diamonds have magnetic characteristics enabling them to act as beacons in MRIs. We effectively turned a pharmaceutical problem into a physics problem.’
Professor Reilly’s team turned its attention to hyperpolarizing nano-diamonds, a process of aligning atoms inside a diamond so they create a signal detectable by an MRI scanner.
‘By attaching hyperpolarized diamonds to molecules targeting cancers the technique can allow tracking of the molecules’ movement in the body,’ says Ewa Rej, the paper’s lead author.
‘This is a great example of how quantum physics research tackles real-world problems, in this case opening the way for us to image and target cancers long before they become life-threatening,’ says Professor Reilly.
The next stage of the team’s work involves working with medical researchers to test the new technology on animals. Also on the horizon is research using scorpion venom to target brain tumours with MRI scanning.

University of Sydneyhttp://tinyurl.com/h8qj2ah