Patients who use a continuous positive airway pressure (CPAP) device to treat obstructive sleep apnea (OSA) often believe that it makes them less sexually attractive, according to researchers at Rosalind Franklin University. A new study abstract released shows that they do not need to worry.
Erectile dysfunction (ED) is common in sleep apnea patients, but studies have shown that the use of CPAP improves ED. However, patients using CPAP may believe that the use of CPAP will have a negative influence on sexual quality, which can in turn make them less likely to use CPAP. Researchers conducted a survey to determine if sexual quality of life (SQOL) differs between CPAP-compliant and noncompliant patients. Patients were deemed to be compliant if they used CPAP more than 4 hours per night for 70% of days.
In this study, 52 patients with OSA on CPAP answered 10 questions pertaining to physical and emotional aspects of lovemaking. Of the 52 patients, 27 were compliant with CPAP, 25 were not. Both groups were similar in age, body mass index, ED, use of medication to treat erectile dysfunction, and presence of depression. Results showed that, when adjusting for all confounding variables, CPAP compliance does not predict sexual quality of life.

A research paper confirms earlier findings that a procedure called endovascular therapy (ET) for ischemic stroke is the best treatment option for many patients by reducing the incidence of disability. This is the fourth research paper published this year that confirms the efficacy of the treatment.

Endometrial cancer (EC) can spread by several routes, including the lymph system, blood vessels, through the uterine wall, as well as through the fallopian tubes into the peritoneal cavity, but the association of transtubal dissemination of EC with cancer stage, histological type, and mortality is unknown. However, according to a study women who have undergone a tubal ligation (TL) and develop more aggressive types of EC may have lower mortality. The authors postulate that women who have had TL have reduced passage of cancer cells through the fallopian tubes, thus lowering disease stage, which is a strong prognostic factor.

To investigate the possible relationship between TL and EC outcomes, Ashley Felix, Ph.D., of the Hormonal and Reproductive Epidemiology Branch, Division of Cancer Epidemiology and Genetics and Cancer Prevention Fellowship Program, Division of Cancer Prevention, National Cancer Institute, Bethesda, MD, and colleagues analyzed data from the multi-institutional NRG Oncology/Gynecologic Oncology Group 210 trial conducted between September 2003 and December 2011. They assessed the history and outcomes for 4489 women diagnosed with EC, including TL, stage, metastasis, and mortality.

About 28% of the women reported having TL at a median age of 32 years. The researchers found that EC patients who also had TL were less likely to have stage III or IV EC across all subtypes of the disease. They were also less likely to have peritoneal metastasis, even if they had more aggressive EC types (high-grade endometrial or serous carcinoma). Metastases to the fallopian tubes, ovaries, parametrium, and bladder/bowel were also inversely associated with TL. However, when adjusted for stage, TL was not associated with disease-specific or overall mortality, except for clear cell EC. This suggests that the mortality benefit was related to inhibiting dissemination of cancer cells through the fallopian tubes.

A limitation of the study, Felix et al. note, is lack of information on types of TL procedures, which have changed over time. Newer methods such as mechanical clips or tubal implants may have a different effect from older ones such as partial excision of tubal segments. However, the authors write that ‘…our study provides evidence that transtubal spread is an important mechanism of metastasis for aggressive histological types of endometrial carcinoma and that this process can be inhibited by TL.’ EurekAlert

Researchers at the Sahlgrenska Academy have shown that a weak electric