The best remedy for severe salicylate poisoning is haemodialysis, according to a comprehensive systematic review of the medical literature. Salicylate is an active ingredient in aspirin as well as hundreds of over-the-counter medications, and contributes to approximately 20,000 accidental or intentional poisonings and nearly 30 deaths reported to US Poison Control Centers every year.
Lung cancer patients who used statins in the year prior to a lung cancer diagnosis or after a lung cancer diagnosis had a reduction in the risk of death from the disease, according to a study.
Endometrial cancer (EC) can spread by several routes, including the lymph system, blood vessels, through the uterine wall, as well as through the fallopian tubes into the peritoneal cavity, but the association of transtubal dissemination of EC with cancer stage, histological type, and mortality is unknown. However, according to a study women who have undergone a tubal ligation (TL) and develop more aggressive types of EC may have lower mortality. The authors postulate that women who have had TL have reduced passage of cancer cells through the fallopian tubes, thus lowering disease stage, which is a strong prognostic factor.
To investigate the possible relationship between TL and EC outcomes, Ashley Felix, Ph.D., of the Hormonal and Reproductive Epidemiology Branch, Division of Cancer Epidemiology and Genetics and Cancer Prevention Fellowship Program, Division of Cancer Prevention, National Cancer Institute, Bethesda, MD, and colleagues analyzed data from the multi-institutional NRG Oncology/Gynecologic Oncology Group 210 trial conducted between September 2003 and December 2011. They assessed the history and outcomes for 4489 women diagnosed with EC, including TL, stage, metastasis, and mortality.
About 28% of the women reported having TL at a median age of 32 years. The researchers found that EC patients who also had TL were less likely to have stage III or IV EC across all subtypes of the disease. They were also less likely to have peritoneal metastasis, even if they had more aggressive EC types (high-grade endometrial or serous carcinoma). Metastases to the fallopian tubes, ovaries, parametrium, and bladder/bowel were also inversely associated with TL. However, when adjusted for stage, TL was not associated with disease-specific or overall mortality, except for clear cell EC. This suggests that the mortality benefit was related to inhibiting dissemination of cancer cells through the fallopian tubes.
A limitation of the study, Felix et al. note, is lack of information on types of TL procedures, which have changed over time. Newer methods such as mechanical clips or tubal implants may have a different effect from older ones such as partial excision of tubal segments. However, the authors write that ‘…our study provides evidence that transtubal spread is an important mechanism of metastasis for aggressive histological types of endometrial carcinoma and that this process can be inhibited by TL.’ EurekAlert
Researchers at the Sahlgrenska Academy have shown that a weak electric
When a hospital patient
Antiretroviral therapy (ART) for HIV infection provides lasting protection against the sexual transmission of the virus from infected men and women to their HIV-uninfected sexual partners, investigators from the HIV Prevention Trials Network (HPTN) reported today at the 8th International AIDS Society (IAS) Conference on HIV Pathogenesis, Treatment and Prevention in Vancouver, Canada. The study, known as HPTN 052, began in 2005 and enrolled 1,763 HIV sero-discordant couples
Removing more tissue during a partial mastectomy could spare thousands of breast cancer patients a second surgery, according to a Yale Cancer Center study.
Nearly 300,000 women in the United States are diagnosed with breast cancer each year; more than half undergo breast-conserving surgery with a partial mastectomy to remove the disease. However, between 20% and 40% of patients who undergo this procedure have
The technology for creating new tissues from stem cells has taken a giant leap forward. Two tablespoons of blood are all that is needed to grow a brand new blood vessel in just seven days. This is shown in a new study from Sahlgrenska Acadedmy and Sahlgrenska University Hospital.
Just three years ago, a patient at Sahlgrenska University Hospital received a blood vessel transplant grown from her own stem cells.
Suchitra Sumitran-Holgersson, Professor of Transplantation Biology at Sahlgrenska Academy, and Michael Olausson, Surgeon/Medical Director of the Transplant Center and Professor at Sahlgrenska Academy, came up with the idea, planned and carried out the procedure. Professors Sumitran-Holgersson and Olausson have published a new study based on two other transplants that were performed in 2012 at Sahlgrenska University Hospital. The patients, two young children, had the same condition as in the first case
Treatment with inhaled nitric oxide (NO) has proven to be life saving in newborns, children and adults with several dangerous conditions, but the availability of the treatment has been limited by the size, weight and complexity of equipment needed to administer the gas and the therapy
Patients with liver cancer can be cured with a liver transplant. But because of the shortage of donated organs, these patients often die waiting for a liver. That
Beukenlaan 137
5616 VD Eindhoven
The Netherlands
+31 85064 55 82
info@interhospi.com
PanGlobal Media IS not responsible for any error or omission that might occur in the electronic display of product or company data.
