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Archive for category: E-News

E-News

Removing more tissue during breast cancer surgery reduces by half the need for second procedure

, 26 August 2020/in E-News /by 3wmedia

Removing more tissue during a partial mastectomy could spare thousands of breast cancer patients a second surgery, according to a Yale Cancer Center study.

Nearly 300,000 women in the United States are diagnosed with breast cancer each year; more than half undergo breast-conserving surgery with a partial mastectomy to remove the disease. However, between 20% and 40% of patients who undergo this procedure have

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Growing a blood vessel in a week

, 26 August 2020/in E-News /by 3wmedia

The technology for creating new tissues from stem cells has taken a giant leap forward. Two tablespoons of blood are all that is needed to grow a brand new blood vessel in just seven days. This is shown in a new study from Sahlgrenska Acadedmy and Sahlgrenska University Hospital.
Just three years ago, a patient at Sahlgrenska University Hospital received a blood vessel transplant grown from her own stem cells.
Suchitra Sumitran-Holgersson, Professor of Transplantation Biology at Sahlgrenska Academy, and Michael Olausson, Surgeon/Medical Director of the Transplant Center and Professor at Sahlgrenska Academy, came up with the idea, planned and carried out the procedure. Professors Sumitran-Holgersson and Olausson have published a new study based on two other transplants that were performed in 2012 at Sahlgrenska University Hospital. The patients, two young children, had the same condition as in the first case

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A lightweight, portable system to produce the gas nitric oxide from the air

, 26 August 2020/in E-News /by 3wmedia

Treatment with inhaled nitric oxide (NO) has proven to be life saving in newborns, children and adults with several dangerous conditions, but the availability of the treatment has been limited by the size, weight and complexity of equipment needed to administer the gas and the therapy

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Livers donated after cardiac death safe to use in liver cancer patients

, 26 August 2020/in E-News /by 3wmedia

Patients with liver cancer can be cured with a liver transplant. But because of the shortage of donated organs, these patients often die waiting for a liver. That

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Combined chemotherapy and immunotherapy shows promise for advanced prostate cancers

, 26 August 2020/in E-News /by 3wmedia

Immune cell manipulation plus chemotherapy achieves prostate cancer remission in mouse models where chemotherapy alone fails

Chemotherapy can be very effective against small prostate tumours. Larger prostate tumours, however, accumulate cells that suppress the body

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Scientists identify a potential new treatment for osteoporosis

, 26 August 2020/in E-News /by 3wmedia

Scientists from the Florida campus of The Scripps Research Institute (TSRI) have identified a new therapeutic approach that, while still preliminary, could promote the development of new bone-forming cells in patients suffering from bone loss.

The study focused on a protein called PPARy (known as the master regulator of fat) and its impact on the fate of stem cells derived from bone marrow (

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Early physical rehabilitation in the ICU leads to better patient outcomes

, 26 August 2020/in E-News /by 3wmedia

In a pre- and post-evaluation study, Johns Hopkins Medicine researchers found that quality improvement processes for delivering early physical rehabilitation in an intensive care unit (ICU) were sustained five years later

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Optical resonance-based biosensors designed for medical applications

, 26 August 2020/in E-News /by 3wmedia

A telecommunications engineer of the NUP/UPNA-Public University of Navarre, has designed optical resonance-based biosensors for use in medical applications like, for example, the detecting of celiac disease. Besides achieving greater resolution and sensitivity, the materials used in these devices are much cheaper and more versatile than the ones used in current technologies (mainly gold and noble metals) so they could offer a potential alternative in the design of biomedical sensors.

A biosensor is an instrument that uses biological molecules (bioreceptors) to detect other biological or chemical substances. In this thesis the bioreceptors have been antibodies, biological molecules that the body produces specifically to fight off antigens. An antigen is a substance foreign to the human body; our immune system recognises it as a threat and in the presence of it the body reacts by producing antibodies to identify and neutralise it. What is more, the biosensor is made up of a substrate (where the physical phenomenon that translates the biological reactions into intelligible information takes place) and the immobilisation layer which causes the antibodies to become attached to the substrate.

‘One of the unique features,’ says the author, ‘is that for the substrate we use silicon waveguides on which we generate a specific type of resonance.’ The biosensors designed are based on the movement of the wavelength of the resonances generated on the basis of the quantity of antigens detected. ‘When the antibodies come together with the antigens, there is a minimum change in the wavelength that our biosensors are capable of picking up.’ This is possible thanks to the resolution achieved by these biosensors and their sensitivity, ‘which enables us to see how much resonances shift on the wavelength as the antibody-antigen links increase.’

The work carried out by Abi

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Beat untreatable eczema with arthritis drug

, 26 August 2020/in E-News /by 3wmedia

Researchers at Yale School of Medicine have successfully treated patients with moderate to severe eczema using a rheumatoid arthritis drug recently shown to reverse two other disfiguring skin conditions, vitiligo and alopecia areata. The study is evidence of a potential new era in eczema treatment, they report.

Eczema (atopic dermatitis) is a chronic condition that causes severe itching and leaves the skin red and thickened. It can adversely affect sleep and quality of life. Standard treatments, such as steroid creams and oral medicines, commonly fail to relieve symptoms in patients with moderate to severe eczema.

Based on current scientific models of eczema biology, assistant professor of dermatology Dr. Brett King hypothesized that a drug approved for rheumatoid arthritis, tofacitinib citrate, would interrupt the immune response that causes eczema.

In the new study, King and his colleagues report that treatment with the drug led to dramatic improvement in six patients with moderate to severe eczema who had previously tried conventional therapies without success.

During treatment all six patients reported significant reduction in itch as well as improved sleep. The redness and thickening of the skin diminished, also.

King and fellow Yale dermatologist Dr. Brittany Craiglow had previously shown that tofacitinib citrate regrows hair in patients with an autoimmune-related form of hair loss called alopecia areata. They also published findings reporting the successful treatment of a patient with vitiligo, which can leave widespread irregular white patches all over the body.

The new study suggests that a change in the standard of care for eczema

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Newer, easier to manage medications may not always be the best choice

, 26 August 2020/in E-News /by 3wmedia

If you are over age 75, and taking an anticoagulant, the old standard may be the gold standard, Mayo Clinic researchers and collaborators have determined.

In a study a team of researchers from Mayo Clinic, and other collaborators, showed that for older patients, particularly individuals greater than 75 years of age,  the risk of gastrointestinal (GI) bleeding is 3 to 5 times higher when taking newer anticoagulant medications dabigatran or rivaroxaban compared to when using warfarin.

One of the most common reasons people take anticoagulant medication

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