Revolutionary ‘metamaterial’ has potential to reshape neurosurgery
The development of graphene
The development of graphene
Researchers at the Stanford University School of Medicine have developed two inexpensive adapters that enable a smartphone to capture high-quality images of the front and back of the eye. The adapters make it easy for anyone with minimal training to take a picture of the eye and share it securely with other health practitioners or store it in the patient
A Mayo Clinic review of 47 studies found that 30-day readmissions can be reduced by almost 20 percent when specific efforts are taken to prevent them. Key among these are interventions to help patients deal with the work passed on to them at discharge.
‘Reducing early hospital readmissions is a policy priority aimed at improving quality of care and lowering costs,’ says Aaron Leppin, M.D., a research associate in Mayo Clinic
Scientists reported today the first human recipients of laboratory-grown vaginal organs. A research team led by Anthony Atala, M.D., director of Wake Forest Baptist Medical Center
Using portable ultrasound as a first-line imaging study in kids with suspected appendicitis helps reduce emergency room length of stay and reduces the need for CT scans, according to a team of Mount Sinai researchers. Bedside ultrasound, often referred to as point-of-care ultrasonography, has a specificity of about 94%, meaning that it misses few cases, the Mt. Sinai researchers add.
Siemens
Nanoparticles have a great deal of potential in medicine: for diagnostics, as a vehicle for active substances or a tool to kill off tumours using heat. ETH Zurich researchers have now developed particles that are relatively easy to produce and have a wide range of applications.
If you put your hand over a switched-on torch in the dark, it appears to glow red. This is because long-wavelength red light beams penetrate human tissue more effectively than short-wavelength blue light. ETH Zurich researchers exploit this fact in a new kind of nanoparticles: so-called plasmonic particles, which heat up when they absorb near-infrared light. This could enable them to kill tumour tissue with heat, for instance.
Gold is a popular material for nanoparticles used therapeutically, as it is well tolerated and does not usually trigger any undesirable reactions. In the characteristic ball or sphere shape of nanoparticles, however, gold does not have the necessary properties to work as a plasmonic particle that absorbs sufficiently in the near-infrared spectrum of light to heat up. To do so, it needs to be moulded into a special shape, such as a rod or shell, so that the gold atoms adopt a configuration that starts absorbing near-infrared light, thereby generating heat. Producing such nanorods or nanoshells in sufficient amounts, however, is complex and expensive.
A team of researchers headed by Sotiris Pratsinis, Professor of Particle Technology at ETH Zurich, has now discovered a trick to manufacture plasmonic gold particles in large amounts. They used their existing know-how on plasmonic nanoparticles and made sphere-shaped gold nanoparticles that display the desired near-infrared plasmonic properties by allowing them to be aggregated. Each particle is coated with a silicon dioxide layer beforehand, which acts as a placeholder between the individual spheres in the aggregate. Through the precisely defined distance between several gold particles, the researchers transform the particles into a configuration that absorbs near-infrared light and thus generates heat.
‘The silicon dioxide shell has another advantage’, explains Georgios Sotiriou, first author on the study and, until recently, a postdoc in Pratsinis
Christopher Longhurst was part of a team that found a way to pull information from hospital patients’ electronic medical records to reduce the rate of one type of infection.
A computerised safety checklist that automatically pulls information from patients’ electronic medical records was associated with a threefold drop in rates of one serious type of hospital-acquired infection, according to a study by researchers at the Stanford University School of Medicine and Lucile Packard Children’s Hospital Stanford.
The study, conducted in the hospital’s pediatric intensive care unit, targeted bloodstream infections that begin in central lines
An optical blood oxygen sensor attached to an endoscope is able to identify pancreatic cancer in patients via a simple endoscopic procedure, according to researchers at Mayo Clinic in Florida.
The study shows that the device, which acts like the well-known clothespin-type finger clip used to measure blood oxygen in patients, has a sensitivity of 92 percent and a specificity of 86 percent.
That means, of 100 patients with pancreatic cancer, this sensor would detect 92 of them, based on the findings. And of 100 patients who don
Inflammation has long been considered an integral part of the biological process that leads to deadly scarring in idiopathic pulmonary fibrosis. New research at National Jewish Health, however, suggests that a little inflammation may also be crucial to the healing and repair processes in the lungs. Elizabeth Redente, PhD, assistant professor of cell biology at National Jewish Health, and her colleagues report that the pro-inflammatory cytokine TNF-α can speed recovery of injured lungs and accelerate the resolution of established fibrosis in a mouse model.
‘The role of inflammation in the development of scarring has been hotly debated in recent years,’ said D
‘Idiopathic pulmonary fibrosis is a relentless, progressive scarring of the lungs for which there is no approved medical therapy. The disease has no known cause and patients generally die within three years of diagnosis. Approximately 40,000 Americans die of idiopathic pulmonary fibrosis every year.
Inflammation was long believed to be a precursor and cause of scarring in the lungs. However, anti-inflammatory treatments have shown no positive effect on the progress of the disease. In recent years, some researchers have thought that inflammation may be part of the healing process as well as the scarring of the lungs.
r. Redente.
April 2024
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