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Archive for category: E-News

E-News

Clinical trial shows tongue-controlled wheelchair outperforms popular wheelchair navigation system

, 26 August 2020/in E-News /by 3wmedia

After a diving accident left Jason DiSanto paralysed from the neck down in 2009, he had to learn how to navigate life from a powered wheelchair, which he controls with a sip-and-puff system. Users sip or puff air into a straw mounted on their wheelchair to execute four basic commands that drive the chair. But results from a new clinical study offer hope that sip-and-puff users like DiSanto could gain a higher level of independence than offered by this common assistive technology.
In the study, individuals with paralysis were able to use a tongue-controlled technology to access computers and execute commands for their wheelchairs at speeds that were significantly faster than those recorded in sip-and-puff wheelchairs, but with equal accuracy. This study is the first to show that the wireless and wearable Tongue Drive System outperforms sip-and-puff in controlling wheelchairs. Sip-and-puff is the most popular assistive technology for controlling a wheelchair.
The Tongue Drive System is controlled by the position of the user

https://interhospi.com/wp-content/uploads/sites/3/2020/06/logo-footer.png 44 200 3wmedia https://interhospi.com/wp-content/uploads/sites/3/2020/06/Component-6-–-1.png 3wmedia2020-08-26 14:41:042020-08-26 14:41:10Clinical trial shows tongue-controlled wheelchair outperforms popular wheelchair navigation system

Hope of new treatment for severe asthma patients

, 26 August 2020/in E-News /by 3wmedia

New research from Japan brings hope of a new treatment for asthma patients resistant to corticosteroids. In a study researchers from the RIKEN Center for Integrative Medical Sciences and Keio University in Japan report that a type of lymphocytes called natural helper (NH) cells plays a critical role in corticosteroid resistance and demonstrate that the anti-psychotic drug Pimozide can be used to overcome resistance to steroids in severe asthma patients.
Asthma is a chronic disease characterised by a persistent inflammation of the airways. The condition can be controlled with a moderate dose of inhaled corticosteroids in most patients. However, 5-10% of patients with ‘severe asthma’ respond poorly to a maximal dose of steroids. These patients experience uncontrolled and frequent asthma symptoms that have a profound impact on their quality of life and health care costs. Unveiling the mechanism leading to steroid resistance in these patients is therefore crucial for the development of a new, effective therapy.

T lymphocytes and NH cells in the asthmatic lung produce proteins named interleukin (IL)-5 and IL-13 that are responsible for severe airway inflammation. In asthma patients, inhaled steroids function by suppressing both T lymphocytes and NH cells.
However, in severe asthma patients, another protein called interleukin-33 (IL-33) produced in the airways strongly activates NH cells to produce IL-5 and IL-13, leading to severe airway inflammation.

In the current study, the researchers led by Drs Shigeo Koyasu from RIKEN and Koichiro Asano from Keio University, employed an experimental mouse model for airway inflammation to study the pathway leading to IL-33-mediated NH activation. Their research shows that NH resistance to steroids is induced by the protein thymic stromal lymphopoietin (TSLP), present in the airways of severe asthma patients.

The team tested reagents that block the intracellular signals triggered by TSLP in NH cells. They identified one drug, Pimozide, an approved anti-psychotic drug, that restored the effects of steroids on NH cells.
‘Therefore, administration of Pimozide or related drugs would be an effective treatment in human severe asthmatic patients,’ conclude the authors. RIKEN

https://interhospi.com/wp-content/uploads/sites/3/2020/06/logo-footer.png 44 200 3wmedia https://interhospi.com/wp-content/uploads/sites/3/2020/06/Component-6-–-1.png 3wmedia2020-08-26 14:41:042020-08-26 14:41:18Hope of new treatment for severe asthma patients

Study suggests possibility of selectively erasing unwanted memories

, 26 August 2020/in E-News /by 3wmedia

The human brain is exquisitely adept at linking seemingly random details into a cohesive memory that can trigger myriad associations

https://interhospi.com/wp-content/uploads/sites/3/2020/06/logo-footer.png 44 200 3wmedia https://interhospi.com/wp-content/uploads/sites/3/2020/06/Component-6-–-1.png 3wmedia2020-08-26 14:41:042020-08-26 14:41:25Study suggests possibility of selectively erasing unwanted memories

Merivaara teams up with Barco to introduce cutting-edge integrated operating room solution

, 26 August 2020/in E-News /by 3wmedia

Finnish company Merivaara is launching a new version of its integrated operating room system, OpenOR

https://interhospi.com/wp-content/uploads/sites/3/2020/06/logo-footer.png 44 200 3wmedia https://interhospi.com/wp-content/uploads/sites/3/2020/06/Component-6-–-1.png 3wmedia2020-08-26 14:41:042020-08-26 14:41:06Merivaara teams up with Barco to introduce cutting-edge integrated operating room solution

Nursing scholar helps develop new ostomy care resource

, 26 August 2020/in E-News /by 3wmedia

Nurses caring for ostomy patients will now be equipped with an essential new tool that provides them with the first comprehensive guide to optimise ostomy management and enhance patient safety.
Janice Beitz, a professor at the Rutgers School of Nursing

https://interhospi.com/wp-content/uploads/sites/3/2020/06/logo-footer.png 44 200 3wmedia https://interhospi.com/wp-content/uploads/sites/3/2020/06/Component-6-–-1.png 3wmedia2020-08-26 14:41:042020-08-26 14:41:13Nursing scholar helps develop new ostomy care resource

Injectable ?smart sponge? holds promise for controlled drug delivery

, 26 August 2020/in E-News /by 3wmedia

Researchers have developed a drug delivery technique for diabetes treatment in which a sponge-like material surrounds an insulin core. The sponge expands and contracts in response to blood sugar levels to release insulin as needed. The technique could also be used for targeted drug delivery to cancer cells.

https://interhospi.com/wp-content/uploads/sites/3/2020/06/logo-footer.png 44 200 3wmedia https://interhospi.com/wp-content/uploads/sites/3/2020/06/Component-6-–-1.png 3wmedia2020-08-26 14:41:042020-08-26 14:41:20Injectable ?smart sponge? holds promise for controlled drug delivery

Strong domestic and international support drive growth of MEDICAL FAIR ASIA 2014

, 26 August 2020/in E-News /by 3wmedia

In just four months, Singapore will once again play host to MEDICAL FAIR ASIA, as it makes a much anticipated return on 9 to 11 September 2014 at Suntec Singapore. The 10th edition of the international exhibition on Hospital, Diagnostic, Pharmaceutical, Medical & Rehabilitation Equipment & Supplies continues its tradition of show-on-show growth, with an expected 25% increase in exhibitors from its 2012 edition.
Extremely positive exhibitor response has resulted in a marked increase in space bookings received, which sees the show expand across two exhibition levels to meet the growing demand for floor space. Further driving this growth is the strong support received in the international arena, with new and returning nations Italy, Spain, Hungary, Turkey and The Netherlands showing keen interest in joining a broad line-up of country pavilions which already include Germany, Austria, France, UK, USA, China, Taiwan, Singapore, Korea, Japan and Malaysia.
Organized by Messe Dusseldorf Asia, Medical Fair Asia brings
together all facets of the medical and healthcare industry for networking, sharing of best industry practices, as well as product, service and solutions development. Part of MEDICA

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Panel issues exercise recommendations for people with osteoporosis and spine fractures

, 26 August 2020/in E-News /by 3wmedia

Experts from the Too Fit to Fracture Initiative presented the results of an international consensus process to establish exercise recommendations for people with osteoporosis, with or without spine fractures. The results were presented at the World Congress on Osteoporosis, Osteoarthritis and Musculoskeletal Diseases in Seville, Spain.

Using the Grading of Recommendations Assessment, Development and Evaluation (GRADE) method, the international multidisciplinary panel examined literature on exercise effects on: 1) falls, fractures, BMD, and adverse events for individuals with osteoporosis or spine fractures; and 2) pain, quality of life, and physical function after spine fracture. Evidence was rated as high, moderate, low, or very low.

In addition, a consensus process was used to established recommendations on assessment, exercise, and physical activity in the context of three cases with varying risk – one having osteoporosis based on bone density; one having osteoporosis and 1 spine fracture; and one having osteoporosis and multiple spine fractures, hyperkyphosis and pain.

The panel recommends that all individuals with osteoporosis should engage in a multicomponent exercise programme that includes resistance and balance training; they should not engage in aerobic training to the exclusion of resistance or balance training.

Other key points included:
current national physical activity guidelines are appropriate for individuals with osteoporosis in the absence of spine fracture, but not for those with spine fracture;
after spine fracture, aerobic activity of moderate intensity is preferred to vigorous; physical therapy consultation is recommended;
daily balance training and endurance training for spinal extensor muscles are recommended for all individuals with osteoporosis;
restrictions are a disincentive to activity participation, and for people with osteoporosis but no history of spine fracture, desired activities should be encouraged if they can be performed safely or modified;
health care providers should provide guidance on safe movement, rather than providing generic restrictions (e.g., lifting);
physical or occupational therapist consult is recommended for advice on exercise and physical activity among those with a history of spine fracture, particularly in the presence of balance or posture impairments, pain, comorbid conditions or that increase the risk of adverse events with exercise or activity, or unsafe movement patterns.

Lead author Dr Lora Giangregorio, University of Waterloo, Waterloo, Canada, stated, ‘People with osteoporosis and spinal fractures should be encouraged to participate in resistance training and balance training, as the strongest evidence we have supports multimodal exercise programs. We have developed evidence-based recommendations, as well as a report that addresses the ‘frequently asked questions’ of patients and health care providers around physical activity. We hope that the recommendations are helpful to health professionals worldwide as they guide their osteoporosis patients in safe, effective – and enjoyable – exercise regimens.’ International Osteoporosis Foundation

https://interhospi.com/wp-content/uploads/sites/3/2020/06/logo-footer.png 44 200 3wmedia https://interhospi.com/wp-content/uploads/sites/3/2020/06/Component-6-–-1.png 3wmedia2020-08-26 14:40:372020-08-26 14:40:51Panel issues exercise recommendations for people with osteoporosis and spine fractures

Molecular pathway linking ICU ventilation to brain damage

, 26 August 2020/in E-News /by 3wmedia

At least 30 percent of patients in intensive care units (ICUs) suffer some form of mental dysfunction as reflected in anxiety, depression, and especially delirium. In mechanically-ventilated ICU patients, the incidence of delirium is particularly high, about 80 percent, and may be due in part to damage in the hippocampus, though how ventilation is increasing the risk of damage and mental impairment has remained elusive.  A new study found a molecular mechanism that may explain the connection between mechanical ventilation and hippocampal damage in ICU patients.  
The investigators, including Adrian Gonz

https://interhospi.com/wp-content/uploads/sites/3/2020/06/logo-footer.png 44 200 3wmedia https://interhospi.com/wp-content/uploads/sites/3/2020/06/Component-6-–-1.png 3wmedia2020-08-26 14:40:372020-08-26 14:40:59Molecular pathway linking ICU ventilation to brain damage

‘eNose’ that sniffs out prostate cancer shows promise

, 26 August 2020/in E-News /by 3wmedia

New research from Finland suggests in the not-too-distant future we may be making rapid, early diagnoses of prostate cancer using a non-invasive electronic nose that sniffs a urine sample.
Researchers from the University of Tampere describe how the ‘eNose’ successfully differentiated between prostate cancer and benign prostatic hyperplasia (BPH) by analysing the ‘smell print’ of the headspace of a urine sample (the air immediately above the urine).
The team says the results from the eNose are comparable to those obtained from prostate specific antigen (PSA) tests.
Prostate cancer is the second most common cancer in men and one of the leading causes of death from cancer. It is not easy to diagnose and make reliable prognoses about prostate cancer because it does not appear consistently in prostate tissue.
Currently, doctors rely on the digital rectal exam (DRE) and the PSA test to help decide if a biopsy is necessary. But these can be hit and miss, while biopsies are costly and uncomfortable, and carry the risk of infection. The other problem with current methods is that many diagnosed prostate cancers will not become life-threatening, and aggressive treatment risks reducing quality of life without extending it.
Odour sampling begins to show promise as a diagnostic for cancer
There have been experiments to test dogs’ ability to sniff out cancer, but scientists have noticed a lot of variation in their performance between and during studies.

About 20 or so years ago, researchers became interested in reports that dogs were detecting cancer in their owners, and since then there have been experiments to test dogs’ ability to sniff out cancer.
For example, in 2010, a scientific meeting of the American Urological Association learned how researchers in Paris had trained dogs to sniff out prostate cancer. They showed the dogs could detect certain prostate cancer cell-derived volatile organic compounds (VOCs) in urine.
However, as more research has been done using dogs, so scientists have noticed a lot of variation in their performance between and during studies, so their findings have limited application.
A more promising avenue is the growth of labs working on the electronic equivalent of sniffer dogs – artificial olfaction or electronic nose technology. For instance, in 2012 we were taken behind the scenes of an electronic nose lab at the California Institute of Technology, and learned how investigators in that lab foresee that one day we will be using smartphones to sniff out diseases.
Electronic noses or ‘eNoses’ that analyse complex mixtures of gas molecules are already used in food and agriculture quality control, and in military applications.
Exhaled air is a ‘problematic sampling material’
eNoses are already being investigated for medical use, including early detection of cancer from exhaled air, says lead investigator Dr. Niku Oksala, of the Department of Surgery in the School of Medicine at the University.
‘However, exhaled air is a problematic sample material since it requires good cooperation and technique from the patient and immediate analysis,’ notes Dr. Oksala, who is also of the Department of Vascular Surgery, Tampere University Hospital.
He points out that urine, on the other hand, is simple to obtain and easy to store, and more feasible for use in clinical practice. Plus, he says:
‘Preliminary data suggested that detection of urologic malignancies from urine headspace was possible. Our own preliminary results on prostate cancer cells encouraged us to launch this prospective clinical study.’ MNT

https://interhospi.com/wp-content/uploads/sites/3/2020/06/logo-footer.png 44 200 3wmedia https://interhospi.com/wp-content/uploads/sites/3/2020/06/Component-6-–-1.png 3wmedia2020-08-26 14:40:372020-08-26 14:40:46‘eNose’ that sniffs out prostate cancer shows promise
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