A unified computational framework developed at Carnegie Mellon University enables clinicians to analyse all major epileptic biomarkers within a single system, potentially transforming presurgical evaluation for drug-resistant epilepsy patients. The spatial-temporal-spectral imaging approach achieves localisation accuracy within millimetres of invasive monitoring whilst eliminating the need for separate analysis pipelines.
Researchers have developed CytoDiffusion, a diffusion-based generative classifier that surpasses clinical experts in blood cell image analysis. The system demonstrates remarkable capabilities in anomaly detection, uncertainty quantification and domain adaptation whilst generating synthetic images indistinguishable from real samples.
Researchers have identified five fundamental genetic factors that explain the majority of genetic risk across 14 psychiatric conditions, based on DNA data from over one million people. The findings challenge current diagnostic boundaries and suggest psychiatric disorders arise from shared biological pathways that manifest differently across conditions, potentially informing more targeted therapeutic development.
A groundbreaking global study reveals that intimate partner violence and sexual violence against children rank among the top health threats worldwide, contributing to over 50 million disability-adjusted life years annually. The research fundamentally challenges persistent views of these forms of violence as primarily social issues, positioning them instead as critical public health priorities demanding immediate, […]
Medical technology start-ups face mounting pressure to navigate complex regulatory frameworks whilst maintaining innovation momentum, according to a newly published white paper from TÜV SÜD. The document, released today, provides structured guidance for young companies seeking to avoid common compliance pitfalls that can delay market entry by months.
A multicentre trial has demonstrated that patients receiving stem cell transplants from unrelated donors with multiple genetic mismatches can achieve survival rates comparable to those with better-matched donors when using post-transplant cyclophosphamide prophylaxis.
Bayer has revealed results from the QUANTI Pediatric study, adding to the safety and efficacy data of the investigational low-dose MRI gadolinium-based contrast agent (GBCA) gadoquatrane.
Researchers at Oregon State University have developed a novel manganese-based contrast agent for magnetic resonance imaging that demonstrates superior performance to current gadolinium-based agents whilst offering improved biocompatibility and reduced environmental concerns. The material, designated BVR-19, represents the first application of metal-organic framework technology incorporating the amino acid L-cystine for medical imaging applications.
Researchers at UMC Utrecht have developed two novel antibodies that specifically target the high-affinity IgG receptor FcγRI, offering a potential therapeutic approach for autoimmune diseases including rheumatoid arthritis, systemic lupus erythematosus, and immune thrombocytopenia. The antibodies, designated C01 and C04, effectively block immune complex binding without triggering receptor activation, addressing a key limitation of previous […]
Researchers in Japan have developed a breakthrough non-invasive closed-loop spinal stimulation system that enables individuals with paraplegia to regain control of leg stepping movements. The hand-controlled magnetic stimulation technique bypasses spinal cord lesions and strengthens preserved neural circuits, offering a surgical-free alternative for gait rehabilitation after spinal cord injury.
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