COMBINEDBrain and the Medical University of South Carolina have announced a strategic collaboration to establish what they describe as the first biorepository dedicated to paediatric central nervous system tissue and cerebrospinal fluid from neurotypical donors, addressing a significant gap in neurological disease research infrastructure.
Researchers have identified dendritic nanotubes – ultrathin connections between neurons that can transport disease-related proteins. The structures, distinct from conventional synapses, may accelerate toxic protein accumulation in specific brain cells during early Alzheimer’s pathology, offering potential new therapeutic targets.
Researchers have identified GPR133/ADGRD1, a mechanosensitive adhesion G protein-coupled receptor, as a promising therapeutic target for osteoporosis. The receptor responds to both mechanical forces and molecular signals, enhancing bone formation through cAMP-dependent activation of β-catenin signalling. A novel small-molecule agonist significantly alleviated osteoporosis in preclinical models, suggesting potential for clinical development.
A systematic review of patient perspectives reveals that cancer patients prioritise emotional support, optimistic demeanour, and realistic expectation-setting from their surgical oncologists alongside clinical expertise. The research identifies six distinct communication domains that shape patient satisfaction and treatment adherence.
Mayo Clinic has launched Mayo Clinic Platform_Orchestrate, a comprehensive programme designed to accelerate clinical development by providing biopharma and medical device companies with streamlined access to de-identified clinical data, artificial intelligence tools, and international research networks.
Dublin-based medical device company Neuromod Devices has secured critical regulatory approvals that will expand global access to its Lenire tinnitus treatment system. The company announced simultaneous approvals for Medical Device Single Audit Program (MDSAP) certification and EU Medical Device Regulation (MDR) compliance.
Siemens Healthineers has unveiled a photon-counting CT scanner specifically designed for radiation therapy planning, aiming to improve treatment accuracy for cancer patients through enhanced imaging capabilities.
Neusoft Medical Systems has announced that its NeuViz P10 photon-counting CT (PCCT) has received market approval from China’s National Medical Products Administration (NMPA). The system represents the first photon-counting CT approved in China and the world’s first wide-body system equipped with an 8-cm detector.
Researchers have successfully used genome language models to design complete, functional bacteriophage genomes, marking the first generative design of whole living organisms. The breakthrough demonstrates AI’s capacity to access novel evolutionary spaces and create phage cocktails that rapidly overcome bacterial resistance.
Healthcare professionals, business leaders, and innovators from across Asia and beyond will converge at Makuhari Messe for MEDICAL JAPAN 2025 TOKYO to experience an immersive exhibition of medical, elderly care, pharmacy, and healthcare, with over 650 exhibitors and an anticipated 18,000 visitors from October 1 to 3, 2025.
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