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Archive for month: August, 2020
World?s first labinabriefcase
Academics at Loughborough University hope to boost early detection rates of cancer in developing countries with their portable labinabriefcase that can operate even at high temperatures.
Believed to be the first kit of its kind dedicated to the portable measurement of cancer biomarkers, the concept is the brainchild of Dr Nuno Reis, a Lecturer in Chemical Engineering.
The number of people dying from cancer in developing countries is on the increase, partly due to steadily ageing populations, but also due to limited access to proper diagnostic tools. Cancer is a leading cause of death worldwide, accounting for over 8 million deaths per year, and 70% of the world
Nanotechnology could spur new heart treatment for arrhythmia
A new nanoparticle developed by University of Michigan researchers could be the key to a targeted therapy for cardiac arrhythmia, a condition that causes the heart to beat erratically and can lead to heart attack and stroke.
Advances over the past 20 years have made cardiac ablation successful and safe for stopping abnormal heartbeats, called arrhythmias, but it remains highly complex.
In studies conducted on rodents and sheep, the UM team found that the treatment successfully kills the cells that cause cardiac arrhythmia while leaving surrounding cells unharmed.
Cardiac arrhythmia is caused by malfunctions in a certain type of heart muscle cell, which normally helps regulate the heartbeat. Today, the disease is usually treated with drugs, which can have serious side effects. It can also be treated with a procedure called cardiac ablation that burns away the malfunctioning cells using a highpowered laser that
InHouse test kits help motivate parents to reduce allergens
Inhome test kits, coupled with patient education, help parents reduce allergen levels in their homes, according to scientists. The researchers found that parents may become more motivated to participate in allergen reduction interventions, when they can actually see results for themselves.
The scientists specifically looked at dust mites, microscopic relatives of the spider, that live in dust on mattresses, bedding, upholstered furniture, carpets, curtains, and other soft furnishings. Dust mites contain allergens known to trigger symptoms in people who are allergic to them, and especially those with asthma.
Researchers show how new hydrogel can facilitate microsurgery
Skillful surgeons can do amazing things in extremely small places, but finding better ways to suture tiny blood vessels has been an ongoing challenge for even the best.
University of Delaware researchers show how a new peptidebased hydrogel could one day make that reconnection process easier to perform and less likely to fail.
The new process uses a hydrogel developed by Daniel J. Smith. Other collaborators include Katelyn NagySmith, who has recently completed all requirements for her doctorate at UD, and Joel Schneider, who was a professor at UD and now is in the Chemical Biology Laboratory at the National Cancer Institute.
Also part of the study were researchers from Johns Hopkins University School of Medicine and the Department of Electrical and Computer Engineering at Johns Hopkins.
Smith designed the peptide, building on a selfassembling process developed more than a decade ago by Schneider while he was a professor in UD’s Department of Chemistry and Biochemistry, and Darrin Pochan, professor and chair of UD’s Department of Materials Science and Engineering.
NagySmith did the microscopy, using a transmission electron microscope at the National Cancer Institute to show how the fibres change when exposed to ultraviolet light.
The way tiny vessels are reconnected now includes stitches applied in microsurgery. But the tiny, thinwalled vessels are fragile and prone to damage in handling.
The peptidebased hydrogel can be tuned in precise ways with a specific amino acid, allowing the material to change form several times during a procedure
Dead bacteria to kill colorectal cancer
Scientists from Nanyang Technological University (NTU Singapore) have successfully used dead bacteria to kill colorectal cancer cells.
Harvesting the Clostridium sporogenes bacteria found commonly in soil, the NTU team was able to harness the bacteria in its dead form, and its secretions, to destroy colon tumours cells effectively.
Colorectal cancer is the number one cancer in Singapore and the foremost cancer amongst males as stated by Singapore
Sustained remission after treatment with investigational personalized cellular therapy in patient with multiple myeloma
A multiple myeloma patient whose cancer had stopped responding after nine different treatment regimens experienced a complete remission after receiving an investigational personalized cellular therapy known as CTL019 developed by a team at the University of Pennsylvania. The investigational treatment was combined with chemotherapy and an autologous stem cell transplant
Leading cause of blindness could be prevented or delayed
In a major scientific breakthrough, a drug used to treat Parkinson
Implantable wireless devices trigger ? and may block ? pain signals
Building on wireless technology that has the potential to interfere with pain, scientists have developed flexible, implantable devices that can activate
MRI-based screening determines which severe stroke patients should receive endovascular treatment
A Massachusetts General Hospital (MGH)-developed system for determining which patients with severe strokes are most likely to benefit from catheter-based systems for blood clot removal led to a greater percentage of screened patients receiving treatment and to outcomes similar to recent studies that found significant treatment benefits. The research team reports how the precision of their classification system, which combines diffusion MRI with key clinical characteristics, more than doubled the percentage of screened patients who were assigned to and probably benefited from treatment.