{"id":18381,"date":"2024-02-07T19:11:35","date_gmt":"2024-02-07T19:11:35","guid":{"rendered":"https:\/\/interhospi.com\/?p=18381"},"modified":"2024-02-08T13:15:54","modified_gmt":"2024-02-08T13:15:54","slug":"neuroscientists-propose-a-new-model-for-classifying-parkinsons","status":"publish","type":"post","link":"https:\/\/interhospi.com\/neuroscientists-propose-a-new-model-for-classifying-parkinsons\/","title":{"rendered":"Researchers call for a neurological disease paradigm shift"},"content":{"rendered":"
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Researchers call for a neurological disease paradigm shift<\/h1>\/ in Featured Articles<\/a> <\/span><\/span><\/header>\n<\/div><\/section><\/p>\n

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Early disease identification<\/h4>\n

The authors argue that for research purposes, patients should be classified by the presence or absence of these three factors. This would allow the identification of Parkinson\u2019s patients before symptoms appear, and aid the development of treatments tailored to patients\u2019 unique biology. Right now, patients are diagnosed based on symptoms and signs, even though the disease may have been present in their brain for many years . By shifting classification criteria, researchers can identify disease earlier (even before people may experience symptoms), and target specific patient groups that have more in common with each other biologically, giving drug development a higher chance of success.<\/p>\n

\u201cAlthough this is still for research purposes, this is a major shift in thinking,\u201d said Dr Ron Postuma, a clinician-scientist at The Neuro (Montreal Neurological Institute-Hospital) of McGill University and one of the study\u2019s authors. \u201cIf you think of it, it\u2019s quite unusual that we\u2019ve had to wait until Parkinson\u2019s patients have important symptoms before we could make a diagnosis. We don\u2019t wait for someone to feel pain from cancer before we diagnose it. Instead, we detect and diagnose it, hopefully before someone is aware of any symptoms. This research classification is a critical step towards bringing our thinking about
\nParkinson\u2019s into the 21st century.\u201d<\/p>\n

Reference:<\/strong><\/em>
\n1. G\u00fcnter U. H\u00f6glinger et al. A biological classification of Parkinson\u2019s disease: the SynNeurGe research diagnostic criteria. The Lancet Neurology. Jan. 22, 2024. doi: https:\/\/doi.org\/10.1016\/S1474-4422(23)00404-0<\/a><\/em><\/p>\n<\/div><\/section>
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