A novel soft robotic device has enabled emergency medical personnel to achieve intubation success rates as high as 96% with only five minutes of training, according to new research published in Science Translational Medicine. The vine-like device could dramatically expand access to life-saving airway management in emergency situations and resource-limited settings.
Scientists have engineered a portable 3D printing device that produces bone grafts directly onto fractures during surgery. The technology enables real-time fabrication of customised implants without pre-operative preparation, whilst incorporating antibiotics to prevent infection and promoting natural bone regeneration at the grafting site.
Comprehensive cardiac monitoring reveals that low aerobic fitness and advancing age independently drive irregular heartbeat patterns previously dismissed as benign, with implications for preventive screening strategies starting at age 50.
Researchers from the International Brain Laboratory have unveiled the first brain-wide activity map showing how decision-making unfolds across the entire brain in mice at single-cell resolution. The comprehensive study recorded from over 621,000 neurons across 279 brain areas, revealing that decision-making is distributed across many regions in a highly coordinated way.
A major international clinical trial has overturned four decades of standard cardiac care, finding that beta-blockers provide no benefit for most heart attack survivors with preserved heart function. The REBOOT study, involving over 8,500 patients, could reshape treatment guidelines worldwide.
The Society of Nuclear Medicine and Molecular Imaging has unveiled a comprehensive digital platform designed to streamline patient access to radiopharmaceutical clinical trials. The Global Radiopharmaceutical Trial Finder utilises artificial intelligence to match patients, physicians, and researchers with relevant studies across multiple international registries, addressing critical gaps in clinical trial participation rates.
A groundbreaking diagnostic test measuring brain blood flow dynamics has demonstrated superior accuracy in detecting Alzheimer’s disease compared to traditional markers, achieving a 96% diagnostic performance rate. The non-invasive cerebrovascular test offers hope for earlier, more accessible dementia screening whilst challenging conventional amyloid-focused diagnostic approaches.
Researchers at the University of Minnesota Twin Cities have demonstrated a groundbreaking process that combines 3D printing, stem cell biology, and lab-grown tissues for spinal cord injury recovery. The innovative approach uses microscopic channels to guide neural regeneration, offering new hope for treating complete spinal cord injuries.
Researchers have developed PathoPlex, a new multiplexed imaging technology capable of mapping over 140 proteins within cells at subcellular resolution. The framework identified kidney stress-related protein patterns in people with type 2 diabetes before clinical signs of disease appeared, potentially accelerating both diagnosis and treatment timelines.
Researchers have achieved a milestone in xenotransplantation by successfully transplanting a genetically modified pig lung into a brain-dead human recipient, where it remained viable and functional for nine days without hyperacute rejection or infection, according to research published in Nature Medicine.
April 2024
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David Haggerty, Marvin Wayne, and James Cazzoli
Device / Jeon et al. 
Dan Birman, International Brain Laboratory
McAlpine Research Group, University of Minnesota