Researchers present a comprehensive framework linking Arctic and Antarctic transformations to worldwide disease burden, from vector-borne illnesses to cardiovascular mortality, urging urgent interdisciplinary action to integrate polar tipping points into health impact assessments and clinical preparedness strategies.
The European Association for the Study of Obesity has released comprehensive guidance positioning semaglutide and tirzepatide as primary treatments for obesity and most complications. The framework, published in Nature Medicine, represents a paradigm shift towards complication-focused prescribing rather than weight loss alone, with recommendations based on systematic meta-analysis of randomised controlled trials.
A simple nursing assessment of patient-reported breathlessness during hospitalisation can identify those at dramatically elevated risk of death, with post-admission dyspnoea linked to a sixfold increase in mortality compared with patients reporting no breathing difficulty, according to research published in ERJ Open Research.
Researchers at University College London have developed NextBrain, a probabilistic histological atlas of the entire human brain that enables automated segmentation of magnetic resonance imaging scans into 333 distinct regions of interest. Built from approximately 10,000 histological sections across five brain hemispheres, the atlas combines artificial intelligence-enabled registration techniques with Bayesian segmentation methods to provide […]
The European Union has initiated funding for the European Research Institute on Simulation (ERIS), a coordinated effort to address the fragmentation of simulation-based medical education across member states. The two-year project, running from 1 May 2025 to 30 April 2027, aims to establish the first pan-European framework for simulation training in interventional cardiac electrophysiology.
A new modelling study analysing 12.8 million bloodstream infections reveals demographic shifts will substantially increase antimicrobial resistance burden by 2030, with men and older adults facing disproportionate risk. Researchers warn even aggressive interventions may fail to meet UN reduction targets for two-thirds of bacteria-antibiotic combinations.
An editorial in the Journal of Intensive Medicine questions the rigid 30 mL/kg fluid resuscitation guideline for septic shock patients, arguing that individualised treatment strategies based on patient-specific factors could improve outcomes whilst reducing risks associated with excessive fluid administration in this life-threatening emergency condition.
Researchers at the University of Macau and University of Hong Kong have developed an innovative multichamber capsule robot that selectively samples bodily fluids and delivers targeted medications via magnetic field control. This breakthrough addresses fundamental limitations in current capsule endoscopy by enabling integrated diagnosis and treatment through single oral administration.
Redefining prostate cancer diagnosis and care Bayer has outlined an ambitious new vision for transforming prostate cancer care globally, emphasizing innovation in imaging, early detection, and patient-centered treatment strategies. Presented ahead of the European Society for Medical Oncology (ESMO) 2025 Congress, the initiative reflects Bayer’s commitment to redefining standards in oncology and radiology through scientific […]
A wireless subretinal photovoltaic implant paired with augmented-reality glasses has enabled patients with complete central vision loss from geographic atrophy to read letters, numbers and words, according to results from a European clinical trial published in The New England Journal of Medicine on 20 October 2025.
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Parts of Figure c and d were produced using images from Smart Servier Medical Art (CC BY 4.0).
Moorfields Eye Hospital